Prolactin Attenuates Neuroinflammation in LPS-Activated SIM-A9 Microglial Cells by Inhibiting NF-κB Pathways Via ERK1/2.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01087-2
Abstract: Prolactin (PRL) is a pleiotropic hormone with multiple functions in several tissues and organs, including the brain. PRL decreases lesion-induced microgliosis and modifies gene expression related to microglial functions in the hippocampus, thereby providing a… read more here.
Keywords: lps activated; prolactin attenuates; prl; erk1 ... See more keywords
Tizoxanide Inhibits Inflammation in LPS-Activated RAW264.7 Macrophages via the Suppression of NF-κB and MAPK Activation
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-00994-3
Abstract: Tizoxanide is the main active metabolite of nitazoxanide. Nitazoxanide and tizoxanide have a broad-spectrum anti-infective effect, including parasites, bacteria, and virus. In the present study, we investigated the anti-inflammatory effect of tizoxanide on lipopolysaccharide (LPS)-stimulated… read more here.
Keywords: inhibits inflammation; lps activated; inflammation lps; activation ... See more keywords
JAK-STAT-dependent regulation of scavenger receptors in LPS-activated murine macrophages.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.172940
Abstract: In atherosclerosis progression, atherosclerotic plaques develop upon accumulated foam cells derived from macrophages that take up modified low-density lipoprotein (LDL). CD36 and CD204 are the principal scavenger receptors responsible for the uptake of modified LDL.… read more here.
Keywords: lps activated; scavenger receptors; jak stat; cd204 ... See more keywords
Anti-inflammatory effects of higenamine (Hig) on LPS-activated mouse microglia (BV2) through NF-κB and Nrf2/HO-1 signaling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106629
Abstract: Microglia are the most widely equipped protective cells in the brain and play a pivotal role in the development of neurological diseases. Inflammatory response and oxidative stress are critical risk factors in the activation of… read more here.
Keywords: anti inflammatory; lps activated; higenamine hig; hig ... See more keywords
Anti-inflammatory mechanisms of neovestitol from Brazilian red propolis in LPS-activated macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.07.029
Abstract: Abstract Neovestitol is considered one of the main bioactive components of Brazilian red propolis. Neovestitol’s antimicrobial and antioxidant effects have already been demonstrated. Here, neovestitol immune modulatory effects were investigated on LPS activated macrophages. RAW264.7… read more here.
Keywords: red propolis; production; activated macrophages; lps activated ... See more keywords
Açaí (Euterpe oleracea Mart.) presents anti-neuroinflammatory capacity in LPS-activated microglia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Nutritional neuroscience"
DOI: 10.1080/1028415x.2020.1842044
Abstract: INTRODUCTION Neuropsychiatric diseases are responsible for one of the highest burden of morbidity and mortality worldwide. These illnesses include schizophrenia, bipolar disorder, and major depression. Individuals affected by these diseases may present mitochondrial dysfunction and… read more here.
Keywords: anti neuroinflammatory; microglia cells; lps activated; cell cycle ... See more keywords
Immunomodulatory effect of IL-1RA in LPS activated macrophage/dental pulp stem cells co-culture.
Sign Up to like & getrecommendations! Published in 2022 at "International endodontic journal"
DOI: 10.1111/iej.13839
Abstract: AIMS Lipopolysaccharides (LPS) activated human dental pulp stem cells (hDPSCs) and macrophage co-cultures showed downregulated TNF-α secretion that is modulated by hDPSCs through IDO axis, whereas the secretory levels of IL-1β remained unchanged. Therefore, sustained… read more here.
Keywords: culture; dental pulp; pulp stem; pulp ... See more keywords
LPS-Activated Microglial Cell-Derived Conditioned Medium Protects HT22 Neuronal Cells against Glutamate-Induced Ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032910
Abstract: Neuron-glia interactions are essential for the central nervous system’s homeostasis. Microglial cells are one of the key support cells in the brain that respond to disruptions in such homeostasis. Although their participation in neuroinflammation is… read more here.
Keywords: cell; neuronal cells; glutamate induced; ferroptosis ... See more keywords
Dereplication and Quantification of Major Compounds of Convolvulus arvensis L. Extracts and Assessment of Their Effect on LPS-Activated J774 Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030963
Abstract: Convolvulus arvensis is used in Pakistani traditional medicine to treat inflammation-related disorders. Its anti-inflammatory potential was evaluated on hexane, dichloromethane, ethyl acetate, methanol, and aqueous extracts of whole plant on pro-inflammatory mediators in LPS-activated murine… read more here.
Keywords: arvensis; convolvulus arvensis; major compounds; lps activated ... See more keywords
Natriuretic-like Peptide Lebetin 2 Mediates M2 Macrophage Polarization in LPS-Activated RAW264.7 Cells in an IL-10-Dependent Manner
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15040298
Abstract: Snake natriuretic peptide (NP) Lebetin 2 (L2) has been shown to improve cardiac function and reduce fibrosis as well as inflammation by promoting M2-type macrophages in a reperfused myocardial infarction (MI) model. However, the inflammatory… read more here.
Keywords: macrophage polarization; activated raw264; polarization; raw264 cells ... See more keywords