Transcriptomic analysis revealing hepcidin expression in Oryzias melastigma regulated through the JAK-STAT signaling pathway upon exposure to BaP.
Sign Up to like & getrecommendations! Published in 2019 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2018.11.015
Abstract: Our previous study revealed that an antimicrobial peptide hepcidin, can be significantly up-regulated either with LPS challenge or upon exposure to Benzo[a]pyrene (BaP) in red sea bream, but the molecular mechanism involved in whether the… read more here.
Keywords: lps challenge; exposure; jak stat; bap exposure ... See more keywords
Expression profiling of selected miRNAs in equine endometrium in response to LPS challenge in vitro: A new understanding of the inflammatory immune response.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2019.02.006
Abstract: Bacterial infections of the genital tract are the major cause of reproductive failure in the mares. MiRNAs are important regulators of gene expression, mostly through transcriptional and translational regression. We hypothesized that LPS induced aberrant… read more here.
Keywords: selected mirnas; response; lps challenge; response lps ... See more keywords
Transcriptomic characterization of the human segmental endotoxin challenge model
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-51547-0
Abstract: Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy safely induces transient airway inflammation in human lungs. This model enables investigation of pulmonary inflammatory mechanisms as well as pharmacodynamic analysis of investigational drugs. The aim of this… read more here.
Keywords: respiratory diseases; challenge model; model; human segmental ... See more keywords
Effect of carvacrol essential oils on growth performance and intestinal barrier function in broilers with lipopolysaccharide challenge
Sign Up to like & getrecommendations! Published in 2020 at "Animal Production Science"
DOI: 10.1071/an18326
Abstract: The purpose of this study was to evaluate the effects of orally administrated carvacrol essential oils (CEOs) on the function of the intestinal barrier in broilers challenged by lipopolysaccharide (LPS). Eighty 28-day-old Ross 308 broilers… read more here.
Keywords: barrier; lps challenge; intestinal barrier; carvacrol essential ... See more keywords
Yeast cell wall polysaccharides enhanced expression of T helper type 1 and 2 cytokines profile in chicken B lymphocytes exposed to LPS challenge and enzyme treatment
Sign Up to like & getrecommendations! Published in 2020 at "British Poultry Science"
DOI: 10.1080/00071668.2020.1817328
Abstract: ABSTRACT 1. The objective of this study was to investigate the potential immunomodulatory effects of yeast (Saccharomyces cerevisiae) and yeast-derived products treated with a cell wall lytic enzyme mixture on the gene expression of toll-like… read more here.
Keywords: cell wall; treatment; expression; lps challenge ... See more keywords
Modulation of LTCC Pathways by a Melusin Mimetic Increases Ventricular Contractility During LPS-Induced Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "SHOCK"
DOI: 10.1097/shk.0000000000001926
Abstract: ABSTRACT Aim: Sepsis-induced cardiomyopathy is commonplace and carries an increased risk of death. Melusin, a cardiac muscle-specific chaperone, exerts cardioprotective function under varied stressful conditions through activation of the AKT pathway. The objective of this… read more here.
Keywords: function; cardiac function; lps induced; induced cardiomyopathy ... See more keywords
Low Intensity Renal Ultrasound Exposure Reduces Systemic Inflammation Induced by LPS Challenge in Mice
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1370
Abstract: Low-intensity pulsed ultrasound (LIPUS), a procedure historically used to stimulate bone healing and tissue repair, activates the splenic cholinergic anti-inflammatory pathway and ultimately reduces circulating and tissue-specific pro-inflammatory cytokine release if applied to the kidney… read more here.
Keywords: mice; lipus; physiology; lps challenge ... See more keywords
Effect of vitamin D source and amount on vitamin D status and response to endotoxin challenge.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dairy science"
DOI: 10.3168/jds.2022-22354
Abstract: The objectives were to test the effects of dietary vitamin D3 [cholecalciferol (CHOL)] compared with 25-hydroxyvitamin D3 [calcidiol (CAL)] on vitamin D status and response to an endotoxin challenge. Forty-five Holstein bull calves (5 ±… read more here.
Keywords: chol; effect; vitamin; source ... See more keywords
Mice Heterozygous for the Sodium Channel Scn8a (Nav1.6) Have Reduced Inflammatory Responses During EAE and Following LPS Challenge
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.533423
Abstract: Voltage gated sodium (Nav) channels contribute to axonal damage following demyelination in experimental autoimmune encephalomyelitis (EAE), a rodent model of multiple sclerosis (MS). The Nav1.6 isoform has been implicated as a primary contributor in this… read more here.
Keywords: inflammatory responses; lps challenge; nav1; mice ... See more keywords
Integrating Serum Metabolome and Gut Microbiome to Evaluate the Benefits of Lauric Acid on Lipopolysaccharide- Challenged Broilers
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.759323
Abstract: Lauric acid (LA) is a crucial medium-chain fatty acid (MCFA) that has many beneficial effects on humans and animals. This study aimed to investigate the effects of LA on the intestinal barrier, immune functions, serum… read more here.
Keywords: gut; lps challenge; metabolism; lauric acid ... See more keywords
Dietary Bovine Lactoferrin Reduces the Deleterious Effects of Lipopolysaccharide Injection on Mice Intestine
Sign Up to like & getrecommendations! Published in 2024 at "Nutrients"
DOI: 10.3390/nu16234040
Abstract: Background/Objectives: Injection of lipopolysaccharides (LPS) in experimental models induces a systemic inflammatory response that is associated with deleterious effects on intestinal morphology and physiology. In this study, we have studied in female mice the effects… read more here.
Keywords: mice; deleterious effects; lps challenge; bovine lactoferrin ... See more keywords