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   Articles with "lps galn" as a keyword



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Antioxidation, anti‐inflammation and anti‐apoptosis by paeonol in LPS/d‐GalN‐induced acute liver failure in mice

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recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.03.003

Abstract: Abstract To evaluate the hepatoprotective effects and potential mechanisms of paeonol (Pae) against acute liver failure (ALF) induced by lipopolysaccharide (LPS)/d‐galactosamine (d‐GalN) in mice, we examined anti‐oxidative, anti‐inflammatory and anti‐apoptotic activities of Pae. We found… read more here.

Keywords: lps galn; apoptosis; pae; acute liver ... See more keywords
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Hepatoprotective effect of flavonoid-enriched fraction from Cyclocarya paliurus leaves on LPS/D-GalN-induced acute liver failure

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recommendations! Published in 2018 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2018.07.031

Abstract: Abstract This study aimed to investigate the chemical composition and hepatoprotective effect of flavonoid fraction from Cyclocarya paliurus leaves (CPF) on the lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute liver failure (ALF). UPLC-MS analysis revealed that CPF mainly contained… read more here.

Keywords: lps galn; fraction cyclocarya; effect flavonoid; hepatoprotective effect ... See more keywords
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Protective effects of tenuigenin on lipopolysaccharide and d-galactosamine-induced acute liver injury.

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recommendations! Published in 2017 at "Microbial pathogenesis"

DOI: 10.1016/j.micpath.2017.09.051

Abstract: Tenuigenin (TEN), a major active component of polygala tenuifolia root, has been reported to have a number of biological properties, such as anti-oxidative and anti-inflammatory activities. However, the protective effect of TEN on acute liver… read more here.

Keywords: liver injury; lps galn; galn induced; acute liver ... See more keywords
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Humulus japonicus Extracts Protect Against Lipopolysaccharide/d-Galactosamine-Induced Acute Liver Injury in Rats.

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recommendations! Published in 2018 at "Journal of medicinal food"

DOI: 10.1089/jmf.2018.4178

Abstract: It has been described that Humulus japonicus has potential antituberculosis and anti-inflammatory effects. The antiaging activity of H. japonicus extract (HJE) was also examined not only in yeast but also in human fibroblast cells. We… read more here.

Keywords: lps galn; humulus japonicus; hje; liver injury ... See more keywords
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Effect of tumor necrosis factor-α on the expression of the ammonia transporter Rhcg in the brain in mice with acute liver failure

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recommendations! Published in 2018 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-018-1264-8

Abstract: BackgroundAmmonia and tumor necrosis factor-alpha (TNF-α) play important roles in the mechanisms of hepatic encephalopathy (HE). Rhesus glycoprotein C (Rhcg) is important for ammonia transport especially in the kidney. The aim of the present study… read more here.

Keywords: lps galn; tnf; ammonia; rhcg brain ... See more keywords
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Andrographolide ameliorates d-galactosamine/lipopolysaccharide-induced acute liver injury by activating Nrf2 signaling pathway

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.17149

Abstract: Andrographolide (ADH), a diterpenoid lactone extracted from Andrographis paniculata, has been found to have anti-inflammatory and anti-oxidative effects. However, its protective effects and mechanisms on liver injury have not been investigated clearly. This study takes… read more here.

Keywords: lps galn; acute liver; liver injury; injury ... See more keywords
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Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.951521

Abstract: Acute liver failure (ALF) is an unfavorable condition characterized by the rapid loss of liver function and high mortality. Chrysophanol-8-O-glucoside (CPOG) is an anthraquinone derivative isolated from rhubarb. This study aims to evaluate the protective… read more here.

Keywords: lps galn; acute liver; chrysophanol glucoside; cpog ... See more keywords

Chromatin Regulator SRG3 Overexpression Protects against LPS/D-GalN-Induced Sepsis by Increasing IL10-Producing Macrophages and Decreasing IFNγ-Producing NK Cells in the Liver

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22063043

Abstract: We previously showed that ubiquitous overexpression of the chromatin remodeling factor SWItch3-related gene (SRG3) promotes M2 macrophage differentiation, resulting in anti-inflammatory responses in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Since hepatic macrophages are… read more here.

Keywords: sepsis; lps galn; overexpression; srg3 ... See more keywords