Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Lipids"
DOI: 10.1002/lipd.12331
Abstract: The occurrence of atherosclerosis is closely related to inflammation and lipid metabolism disorder. It has been found that lipopolysaccharide (LPS) could induce inflammation, and tyloxapol (Ty) could induce hyperlipidemia. However, the effects of LPS and… read more here.
Keywords: development atherosclerosis; lipid metabolism; mice; atherosclerosis ... See more keywords
Tetramethylpyrazine alleviates LPS-induced inflammatory injury in HUVECs by inhibiting Rho/ROCK pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.135
Abstract: Endothelial dysfunction plays an important role in the pathogenesis of acute lung injury (ALI). Tetramethylpyrazine (TMP) has been reported to attenuate harmful changes in ALI rats. However, the effects of TMP on endothelial cell injury… read more here.
Keywords: inflammatory injury; lps group; group; huvecs ... See more keywords
Prenatal LPS induces sickness behaviour and decreases maternal and predatory behaviours after an LPS challenge
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2019.1706505
Abstract: Abstract Purpose: The influence of a challenge dose of lipopolysaccharide (LPS) on the behavioural selection between maternal (MB) and predatory behaviours (PB) of female rats prenatally treated with the same endotoxin or saline solution (F1… read more here.
Keywords: sickness behaviour; lps group; maternal predatory; group ... See more keywords
Onjisaponin B (OB) is Neuroprotective During Cognitive Loss Through Immune-mediated and SIRT1 Pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Current neurovascular research"
DOI: 10.2174/1567202615666180528071520
Abstract: BACKGROUND The purpose of the present study was to investigate the effects of Onjisaponin B (OB) in lipopolysaccharide (LPS)-induced cognitive deficits. METHODS The rats were divided into four groups: sham group, LPS group (the model… read more here.
Keywords: caspase; lps induced; lps group; group ... See more keywords
Effects of Lipopolysaccharide on Oligodendrocyte Differentiation at Different Developmental Stages: an In Vitro Study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2021.36.e332
Abstract: Background Lipopolysaccharide (LPS) exerts cytotoxic effects on brain cells, especially on those belonging to the oligodendrocyte lineage, in preterm infants. The susceptibility of oligodendrocyte lineage cells to LPS-induced inflammation is dependent on the developmental stage.… read more here.
Keywords: differentiation; group; lps group; developmental stages ... See more keywords
The Effect of Endotoxin on the Intestinal Mucus Layer in Non- and Post-pregnancy Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.824170
Abstract: The intestine is the most extensive storage organ of bacteria and endotoxins, and the mucosal immune system is the first barrier of the intestine. Mucin-2 (MUC2) is the major component of the mucus layers. In… read more here.
Keywords: lps group; mucus; muc2; significantly decreased ... See more keywords
Effects of Citrus kawachiensis Peel in Frailty-like Model Mice Induced by Low Protein Nutrition Disorders
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030779
Abstract: “Frailty” caused by a decline in physiological reserve capacity, chronic inflammation, and oxidative stress in the elderly has recently become a major social issue. The present study examined the effects of the peel of Citrus… read more here.
Keywords: lps group; group; peel; citrus kawachiensis ... See more keywords
[Protective effects of myocardium-targeted nanoparticles loaded L-arginineon on sepsis-induced myocardial injury].
Sign Up to like & getrecommendations! Published in 2020 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20200217-00168
Abstract: OBJECTIVE To prepare primary cardiomyocyte (PCM) specific peptide-conjugated mesoporous silicon nanoparticles (MSN) with L-arginine (LA) as a core (PCM-MSN@LA), and evaluate its specific protective effect on septic myocardium. METHODS PCM-MSN@LA was prepared by condensation reaction,… read more here.
Keywords: msn lps; lps group; group; pcm msn ... See more keywords
[MicroRNA-499 improved septic myocardial dysfunction by regulating myosin heavy chain gene axis].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20210706-01012
Abstract: OBJECTIVE To investigate the role and mechanism of microRNA-499 (miR-499) regulating α-myosin heavy chain (α-MHC) and β-myosin heavy chain (β-MHC) gene axis in septic myocardial dysfunction (SMD) and its significance. METHODS Sixty healthy adult male… read more here.
Keywords: pretreatment; mhc; lps group; expression ... See more keywords
[Protective effect of heat shock transcription factor 1 on acute lung injury in septic rats by regulating NOD-like receptor protein 3 inflammasome activation].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20210930-01417
Abstract: OBJECTIVE To determine whether heat shock transcription factor 1 (HSF1) ameliorates sepsis induced acute lung injury (ALI) by regulating NOD-like receptor protein 3 (NLRP3) inflammasome activity in rat alveolar macrophages (AM). METHODS Twenty-four SPF Sprague-Dawley… read more here.
Keywords: lung tissue; group; hsf1; lps group ... See more keywords
[O-linked N-acetylglucosamine modification induced by lipopolysaccharide is involved in inflammatory signaling pathway in endothelial cells].
Sign Up to like & getrecommendations! Published in 2023 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20220314-00242
Abstract: OBJECTIVE To explore whether the lipopolysaccharide (LPS)-induced modification of O-linked N-acetylglucosamine (O-GlcNAc) is involved in the inflammatory signaling pathway of endothelial cells. METHODS Human umbilical vein endothelial cells (HUVEC) were cultured in vitro, and cells… read more here.
Keywords: modification; endothelial cells; mrna; inhibitor ... See more keywords