LPS‐mediated release of ATP from urothelial cells occurs by lysosomal exocytosis
Sign Up to like & getrecommendations! Published in 2020 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24377
Abstract: While numerous studies have confirmed ATP's importance in bladder physiology/pathophysiology, the literature is still conflicted regarding the mechanism of ATP release from the urothelium. Multiple mechanisms have been identified including non‐vesicular release via pannexin channels… read more here.
Keywords: atp urothelial; release atp; urothelial cells; lps mediated ... See more keywords
γ-Oryzanol suppresses COX-2 expression by inhibiting reactive oxygen species-mediated Erk1/2 and Egr-1 signaling in LPS-stimulated RAW264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.016
Abstract: Cyclooxygenase (COX)-2 produces prostanoids, which contribute to inflammatory responses. Nuclear factor (NF)-κB is a key transcription factor mediating COX-2 expression. γ-Oryzanol is an active component in rice bran oil, which inhibits lipopolysaccharide (LPS)-mediated COX-2 expression… read more here.
Keywords: reactive oxygen; cox expression; egr expression; lps mediated ... See more keywords
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2020.104046
Abstract: Uncontrolled activation of NLRP3 inflammasome initiates a series of human inflammatory diseases. Targeting NLRP3 inflammasome has attracted considerable attention in developing potential therapeutic interventions. Here, we reported that dehydrocostus lactone (DCL), a main component of… read more here.
Keywords: dehydrocostus lactone; inflammation; asc oligomerization; lps mediated ... See more keywords
Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-024-01856-0
Abstract: The key target for treating inflammatory osteolysis is osteoclasts. In an inflammatory environment, osteoclast differentiation increases, and bone resorption is enhanced. Periplogenin (Ppg) is a traditional Chinese medicine. It has anti-inflammatory and antitumor effects, but… read more here.
Keywords: attenuates lps; periplogenin attenuates; lps mediated; inflammatory osteolysis ... See more keywords
SP-D attenuates LPS-induced formation of human neutrophil extracellular traps (NETs), protecting pulmonary surfactant inactivation by NETs
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0662-5
Abstract: An exacerbated amount of neutrophil extracellular traps (NETs) can cause dysfunction of systems during inflammation. However, host proteins and factors that suppress NET formation (NETosis) are not clearly identified. Here we show that an innate… read more here.
Keywords: neutrophil extracellular; formation; pulmonary surfactant; lps mediated ... See more keywords
1,25-Dihydroxy vitamin D3 inhibits LPS-mediated inflammatory responses in endometriosis
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Medicine"
DOI: 10.1080/07853890.2025.2523563
Abstract: Abstract Background Endometriosis, a chronic immune-mediated inflammatory disease, remains elusive in its pathogenesis. Given vitamin D (VD)’s pivotal role in modulating innate and adaptive immune responses, we sought to elucidate how VD modulates inflammatory responses… read more here.
Keywords: ishikawa cells; lps mediated; responses endometriosis; mediated inflammatory ... See more keywords
N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "BMC Neuroscience"
DOI: 10.1186/s12868-017-0399-3
Abstract: BackgroundActivated microglia interact with astrocytes and neuronal cells to induce neuroinflammation, which can contribute to the pathogenesis and progression of Alzheimer’s and Parkinson’s disease. To identify the most effective anti-neuroinflammatory agent, we designed and synthesized… read more here.
Keywords: signaling pathways; apoptosis; neuronal apoptosis; mapk signaling ... See more keywords
The CH 2 Cl 2 Extract Fraction from Ficus erecta var. sieboldii (Miq.) King Suppresses Lipopolysaccharide-mediated Inflammatory Responses in Raw264.7 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Food and Nutrition Research"
DOI: 10.12691/jfnr-6-6-2
Abstract: A phytochemical application of leaves from Ficus erecta var. sieboldii (Miq.) King has not been widely investigated. We determined an anti-inflammatory effect of F. erecta extracts on lipopolysaccharide (LPS)-mediated production through modulation of several pro-inflammatory… read more here.
Keywords: ficus erecta; production; lps mediated; var sieboldii ... See more keywords
LncRNA29RIK in macrophages promotes LPS-mediated sensitivity to obesity
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1574507
Abstract: Lipopolysaccharide (LPS, endotoxin) -mediated signaling of caspase-4 (human) and -11 (rodent) can induce the maturation of inflammatory cytokine IL-1β and cell pyroptosis, which is associated with the pathophysiology of many diseases such as obesity. However,… read more here.
Keywords: lps mediated; obesity; macrophages promotes; sensitivity ... See more keywords
Isolation and Identification of Anti-Inflammatory Peptide from Goose Blood Hydrolysate to Ameliorate LPS-Mediated Inflammation and Oxidative Stress in RAW264.7 Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248816
Abstract: This study was designed to isolate an anti-inflammatory activity oligopeptide from goose blood (GBP) for ameliorating LPS-mediated inflammation response and oxidative stress in RAW264.7 macrophages. In this study, GBP was isolated by tangential flow ultrafiltration… read more here.
Keywords: inflammation; mediated inflammation; oxidative stress; anti inflammatory ... See more keywords