Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
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DOI: 10.1038/s41598-018-31926-0
Abstract: Toll-like receptor 4 (TLR4) is activated by bacterial lipopolysaccharide (LPS), which drives the production of proinflammatory cytokines. Earlier studies have indicated that cholesterol- and glycosphingolipid-rich subregions of the plasma membrane (lipid domains) are important for… read more here.
Keywords: lps induced; glucer; lps tlr4; inflammatory response ... See more keywords
Gypenosides improves nonalcoholic fatty liver disease induced by high-fat diet induced through regulating LPS/TLR4 signaling pathway
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DOI: 10.1080/15384101.2020.1829800
Abstract: ABSTRACT Background The contents of lipopolysaccharide (LPS) and Toll-like receptor 4 (TLR4) are significantly increased during the progression of nonalcoholic fatty liver disease (NAFLD). The study investigated the role of the LPS/TLR4 signaling pathway in… read more here.
Keywords: fatty liver; liver disease; lps tlr4; signaling pathway ... See more keywords
LPS/TLR4 pathways in breast cancer: insights into cell signalling.
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DOI: 10.2174/0929867328666210811145043
Abstract: BACKGROUND Cancer cells are usually recognized as foreign particles by the immune cells. Mounting evidences suggest important link between toll like receptors (TLRs) and carcinogenesis. This review article focused on the role of TLRs, especially… read more here.
Keywords: cancer; lps tlr4; tlr4 pathways; breast cancer ... See more keywords
Dendrobium officinale Polysaccharide Protected CCl4-Induced Liver Fibrosis Through Intestinal Homeostasis and the LPS-TLR4-NF-κB Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00240
Abstract: We explored the therapeutic effects of Dendrobium officinale polysaccharide (DOP) on CCl4-induced liver fibrosis with respect to the intestinal hepatic axis using a rat model. Histopathological staining results showed that DOP alleviated extensive fibrous tissue… read more here.
Keywords: liver fibrosis; lps tlr4; signaling pathway; dendrobium officinale ... See more keywords