Neuropharmacological assessment in mice and molecular docking of piperazine derivative LQFM212
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DOI: 10.1016/j.bbr.2020.112827
Abstract: Piperazine derivatives are an attractive class of chemical compounds for the treatment of various mental illness. Herein, we demonstrated the synthesis of LQFM212, a piperazine derivative, behavioral evaluation in mice and computational studies. In neuropharmacological… read more here.
Keywords: piperazine derivative; neuropharmacological assessment; lqfm212; anxiolytic like ... See more keywords
Potential antidepressant-like effect of piperazine derivative LQFM212 in mice: Role of monoaminergic pathway and brain-derived neurotrophic factor
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DOI: 10.1016/j.bbr.2020.113066
Abstract: Major depression disorder (MDD) is one of the most widespread and debilitating psychiatric diseases and may be associated with other mental disorders such as anxiety. Despite advances in neurobiology studies, currently no established mechanism can… read more here.
Keywords: monoaminergic pathway; lqfm212; like effect; antidepressant like ... See more keywords