Articles with "lqts" as a keyword



Deep Learning-Augmented ECG Analysis for Screening and Genotype Prediction of Congenital Long QT Syndrome.

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Published in 2024 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2024.0039

Abstract: Importance Congenital long QT syndrome (LQTS) is associated with syncope, ventricular arrhythmias, and sudden death. Half of patients with LQTS have a normal or borderline-normal QT interval despite LQTS often being detected by QT prolongation… read more here.

Keywords: deep learning; validation; lqts; congenital long ... See more keywords

Mothers with long QT syndrome are at increased risk for fetal death: Findings from a multicenter international study.

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Published in 2019 at "American journal of obstetrics and gynecology"

DOI: 10.1016/j.ajog.2019.09.004

Abstract: BACKGROUND Most fetal deaths are unexplained. Long QT syndrome (LQTS) is a genetic disorder of cardiac ion channels. Affected individuals, including fetuses, are predisposed to sudden death. We sought to determine the risk of fetal… read more here.

Keywords: death; lqts; study; risk fetal ... See more keywords
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Long QT Syndrome Type 1 and 2 Patients Respond Differently to Arrhythmic Triggers - The TriQarr In Vivo Study.

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Published in 2020 at "Heart rhythm"

DOI: 10.1016/j.hrthm.2020.08.017

Abstract: BACKGROUND In patients with long QT syndrome (LQTS), swimming and loud noises have been identified as genotype-specific arrhythmic triggers in LQTS type 1 and LQTS type 2, respectively. OBJECTIVE To compare LQTS groups' responses to… read more here.

Keywords: lqts2 patients; heart rate; arrhythmic triggers; lqts ... See more keywords
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Diagnostic Accuracy of the 12-Lead Electrocardiogram in the First 48 Hours of Life for Newborns of a Parent with Congenital Long QT Syndrome.

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Published in 2022 at "Heart rhythm"

DOI: 10.1016/j.hrthm.2022.01.041

Abstract: BACKGROUND Long QT syndrome (LQTS) is an autosomal dominant disorder characterized by a prolonged QT interval. ECG screening in the first 48 hours of life may be misleading, even in newborns with a genotype-positive LQTS… read more here.

Keywords: long syndrome; genotype positive; first hours; hours life ... See more keywords

Congenital long QT syndrome presenting as unexplained bradycardia

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Published in 2022 at "BMJ Case Reports"

DOI: 10.1136/bcr-2021-242362

Abstract: Congenital long QT syndrome (LQTS) is a genetically autosomal heterogeneous disorder of the ion channels and causes about 10% of sudden death infant syndrome in newborns. Its estimated prevalence is approximately 1 in 2500, probably… read more here.

Keywords: long syndrome; presenting unexplained; congenital long; unexplained bradycardia ... See more keywords

Abstract 14500: Physical Activity in Individuals With the Long Qt Syndrome: Baseline Data From the Lifestyle and Exercise in Long Qt Study (live Lqts)

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Published in 2020 at "Circulation"

DOI: 10.1161/circ.142.suppl_3.14500

Abstract: Introduction: The safety of vigorous exercise for individuals with appropriately-treated LQTS remains unproven, and physical activity practices in this population have not been described. Methods: LIVE-LQTS prospectively enrolled individuals age 8-60 years with overt LQTS… read more here.

Keywords: vigorous exercise; lqts; live lqts; exercise ... See more keywords

Abstract 4364602: Polygenic background for QT interval influences disease penetrance in individuals with genotype-positive congenital long QT syndrome

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Published in 2025 at "Circulation"

DOI: 10.1161/circ.152.suppl_3.4364602

Abstract: Background: Congenital long QT syndrome (LQTS) is characterized by a prolongation of the heart rate-corrected QT interval (QTc) and an increased risk of syncope, seizure and sudden cardiac arrest/death (SCA/SCD). Genome-wide association studies have identified… read more here.

Keywords: interval; genotype positive; lqts; qtc ... See more keywords

Determination and Interpretation of the QT Interval: Comprehensive Analysis of a Large Cohort of Long QT Syndrome Patients and Controls

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Published in 2018 at "Circulation"

DOI: 10.1161/circulationaha.118.033943

Abstract: Background: Long QT syndrome (LQTS) is associated with potentially fatal arrhythmias. Treatment is very effective, but its diagnosis may be challenging. Importantly, different methods are used to assess the QT interval, which makes its recognition… read more here.

Keywords: long syndrome; lqts; interval; interpretation interval ... See more keywords

Vigorous Exercise in Patients With Congenital Long QT Syndrome: Results of the Prospective, Observational, Multinational LIVE-LQTS Study

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Published in 2024 at "Circulation"

DOI: 10.1161/circulationaha.123.067590

Abstract: BACKGROUND: Whether vigorous exercise increases risk of ventricular arrhythmias for individuals diagnosed and treated for congenital long QT syndrome (LQTS) remains unknown. METHODS: The National Institutes of Health–funded LIVE-LQTS study (Lifestyle and Exercise in the… read more here.

Keywords: long syndrome; lqts; group; congenital long ... See more keywords