Leucine‐Rich Amelogenin Peptide (LRAP) Uptake by Cementoblast Requires Flotillin‐1 Mediated Endocytosis
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DOI: 10.1002/jcp.25453
Abstract: Basic, pre‐clinical, and clinical studies have documented the potential of amelogenin, and its variants, to affect cell response and tissue regeneration. However, the mechanisms are unclear. Thus, the aim of the present study was to… read more here.
Keywords: rich amelogenin; leucine rich; lrap uptake; endocytosis ... See more keywords
Novel LRAP‐binding partner revealing the plasminogen activation system as a regulator of cementoblast differentiation and mineral nodule formation in vitro
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DOI: 10.1002/jcp.29331
Abstract: Amelogenin isoforms, including full‐length amelogenin (AMEL) and leucine‐rich amelogenin peptide (LRAP), are major components of the enamel matrix, and are considered as signaling molecules in epithelial–mesenchymal interactions regulating tooth development and periodontal regeneration. Nevertheless, the… read more here.
Keywords: nodule formation; plasminogen; amelogenin; mineral nodule ... See more keywords