Omitting radiation therapy in women with triple-negative breast cancer leads to worse breast cancer-specific survival.
Sign Up to like & getrecommendations! Published in 2017 at "Breast"
DOI: 10.1016/j.breast.2016.12.007
Abstract: PURPOSE To examine locoregional recurrence (LRR) and breast cancer-specific survival (BCSS) after breast-conserving therapy (BCT) or mastectomy (ME) with or without radiation therapy (RT) in triple-negative breast cancer (TNBC). MATERIAL & METHODS We identified non-metastatic… read more here.
Keywords: breast; group; breast cancer; lrr ... See more keywords
Genomic Alterations and Radioresistance in Breast Cancer: An Analysis of the Profiler Protocol
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Radiation Oncology Biology Physics"
DOI: 10.1016/j.ijrobp.2017.06.132
Abstract: Purpose/Objective(s) Breast cancer (BC) patients with comparable prognostic features have heterogeneous outcomes, partly because of radiotherapy resistance leading to loco-regional recurrences (LRR). The ProfiLER (Profilage LYric et Region, NCT01774409) clinical trial aims at establishing a… read more here.
Keywords: profiler; analysis; breast cancer; lrr ... See more keywords
A Tomato Nucleotide Binding Sites-Leucine-Rich Repeat Gene Is Positively Involved in Plant Resistance to Phytophthora infestans.
Sign Up to like & getrecommendations! Published in 2018 at "Phytopathology"
DOI: 10.1094/phyto-12-17-0389-r
Abstract: The nucleotide binding sites-leucine-rich repeat (NBS-LRR) genes are key regulatory components of plant to pathogens. Phytophthora infestans-inducible coding sequence encoding an NBS-LRR (SpNBS-LRR) protein in tomato (Solanum pimpinellifolium L3708) was cloned and characterized based on… read more here.
Keywords: spnbs lrr; nucleotide binding; tomato; lrr ... See more keywords
MSF-LRR: Multi-Similarity Information Fusion Through Low-Rank Representation to Predict Disease-Associated Microbes
Sign Up to like & getrecommendations! Published in 2022 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2022.3146176
Abstract: An Increase in microbial activity is shown to be intimately connected with the pathogenesis of diseases. Considering the expense of traditional verification methods, researchers are working to develop high-efficiency methods for detecting potential disease-related microbes.… read more here.
Keywords: information; similarity; disease; low rank ... See more keywords
Development and Validation of a Genomic Profile for the Omission of Local Adjuvant Radiation in Breast Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.22.00655
Abstract: PURPOSE Adjuvant radiotherapy (RT) is used for women with early-stage invasive breast cancer treated with breast-conserving surgery. However, some women with low risk of recurrence may safely be spared RT. This study aimed to identify… read more here.
Keywords: validation; breast; breast cancer; risk ... See more keywords
A Dual Leucine-Rich Repeat In Proteins From The Eukaryotic Sar Group.
Sign Up to like & getrecommendations! Published in 2023 at "Protein and peptide letters"
DOI: 10.2174/0929866530666230519160439
Abstract: BACKGROUND Leucine-rich repeats (LRRs) occurring in tandem are 20 ⎼ 29 amino acids long. Eleven LRR types have been recognized; they include plant-specific (PS) type with the consensus of LxxLxLxxNxL SGxIPxxIxxLxx of 24 residues and… read more here.
Keywords: sar group; leucine rich; sds22 like; lrr ... See more keywords
Prognostic Factors and Surgery for Breast Cancer Patients With Locoregional Recurrence: An Analysis of 5,202 Consecutive Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.763119
Abstract: Purpose With the application of “less extensive surgery” in breast cancer treatment, the pattern of locoregional recurrence (LRR) has significantly changed. This study aims to evaluate the risk and prognostic factors of LRR in a… read more here.
Keywords: recurrence; breast; breast cancer; lrr ... See more keywords
Comprehensive analysis of peptide-coding genes and initial characterization of an LRR-only microprotein in Marchantia polymorpha
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1051017
Abstract: In the past two decades, many plant peptides have been found to play crucial roles in various biological events by mediating cell-to-cell communications. However, a large number of small open reading frames (sORFs) or short… read more here.
Keywords: analysis; lrr; mpsgf10b; polymorpha ... See more keywords
Tsw – A case study on structure-function puzzles in plant NLRs with unusually large LRR domains
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.983693
Abstract: Plant disease immunity heavily depends on the recognition of plant pathogens and the subsequent activation of downstream immune pathways. Nod-like receptors are often crucial in this process. Tsw, a Nod-like resistance gene from Capsicum chinense… read more here.
Keywords: function; structure; unusually large; large lrr ... See more keywords
Postoperative Quality Assessment Score Can Select Patients with High Risk for Locoregional Recurrence in Colon Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12020363
Abstract: Background: Monitoring surgical quality has been shown to reduce locoregional recurrence (LRR). We previously showed that the arterial stump length (ASL) after complete mesocolic excision (CME) is a reproducible quality instrument and correlates with the… read more here.
Keywords: quality; locoregional recurrence; high risk; risk ... See more keywords
DeepLRR: An Online Webserver for Leucine-Rich-Repeat Containing Protein Characterization Based on Deep Learning
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11010136
Abstract: Members of the leucine-rich repeat (LRR) superfamily play critical roles in multiple biological processes. As the LRR unit sequence is highly variable, accurately predicting the number and location of LRR units in proteins is a… read more here.
Keywords: leucine rich; lrr rlk; lrr; rich repeat ... See more keywords