Abstract 3269: LRRC15/COL11A1+cancer-associated fibroblasts drive immunosuppression and chemotherapy resistance in pancreatic ductal adenocarcinoma
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DOI: 10.1158/1538-7445.am2025-3269
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a highly immunosuppressive tumor microenvironment (TME), which contributes to immune evasion, chemotherapy resistance, and poor prognosis. Cancer-associated fibroblasts (CAFs) are key components of the TME and are closely… read more here.
Keywords: cancer; col11a1; col11a1 cafs; lrrc15 col11a1 ... See more keywords