LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation
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DOI: 10.7554/elife.59704
Abstract: The NLRP3 inflammasome is a multi-molecular protein complex that converts inactive cytokine precursors into active forms of IL-1β and IL-18. The NLRP3 inflammasome is frequently associated with the damaging inflammation of non-communicable disease states and… read more here.
Keywords: activation; induced nlrp3; lrrc8a essential; nlrp3 inflammasome ... See more keywords