Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation
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DOI: 10.1038/s42003-020-0951-z
Abstract: Members of the leucine-rich repeat-containing 8 (LRRC8) protein family, composed of the five LRRC8A-E isoforms, are pore-forming components of the volume-regulated anion channel (VRAC). LRRC8A and at least one of the other LRRC8 isoforms assemble… read more here.
Keywords: lrrc8d isoform; regulated anion; isoform; structure ... See more keywords