Possible association between the lrrk2 gene and anxiety behavior: a systematic literature review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurogenetics"
DOI: 10.1080/01677063.2022.2144293
Abstract: Abstract Alterations to the LRRK2 gene have been associated with Parkinson’s disease and alcohol consumption in animals and humans. Furthermore, these disorders are strongly related to anxiety disorders (ADs). Thus, we investigated how the LRRK2… read more here.
Keywords: review; lrrk2; lrrk2 gene; anxiety ... See more keywords
LRRK2 Gene Variants Associated With a Higher Risk for Alcohol Dependence in Multiethnic Populations
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.665257
Abstract: Background: Genetics influence the vulnerability to alcohol use disorders, and among the implicated genes, three previous studies have provided evidences for the involvement of LRRK2 in alcohol dependence (AD). LRRK2 expression is broadly dysregulated in… read more here.
Keywords: risk; lrrk2 gene; alcohol dependence; multiethnic populations ... See more keywords
Advances in Gene Therapy Techniques to Treat LRRK2 Gene Mutation
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12121814
Abstract: Leucine-rich repeat kinase 2 (LRRK2) gene mutation is an autosomal dominant mutation associated with Parkinson’s disease (PD). Among LRRK2 gene mutations, the LRRK2 G2019S mutation is frequently involved in PD onset. Currently, diverse gene correction… read more here.
Keywords: gene mutation; lrrk2 g2019s; gene therapy; lrrk2 gene ... See more keywords
High-Throughput Sequencing Haplotype Analysis Indicates in LRRK2 Gene a Potential Risk Factor for Endemic Parkinsonism in Southeastern Moravia, Czech Republic
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12010121
Abstract: Parkinson’s disease and parkinsonism are relatively common neurodegenerative disorders. This study aimed to assess potential genetic risk factors of haplotypes in genes associated with parkinsonism in a population in which endemic parkinsonism and atypical parkinsonism… read more here.
Keywords: parkinsonism; lrrk2 gene; high throughput; risk ... See more keywords