LRRK2 Loss‐of‐Function Variants: When Less Is More
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DOI: 10.1002/mds.28291
Abstract: Gain-of-function variants in leucine-rich repeat kinase 2 (LRRK2) are the most common monogenic cause of Parkinson’s disease (PD), albeit with incomplete penetrance, indicating that reduction of LRRK2 kinase activity is a reasonable therapeutic strategy for… read more here.
Keywords: lof variants; lrrk2 lof; function variants; lrrk2 ... See more keywords