Modeling Parkinson's disease in LRRK2 mice: focus on synaptic dysfunction and the autophagy-lysosomal pathway.
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DOI: 10.1042/bst20211288
Abstract: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are associated with familial and sporadic forms of Parkinson's disease (PD), for which the LRRK2 locus itself represents a risk factor. Idiopathic and LRRK2-related PD share… read more here.
Keywords: lrrk2 mutants; lysosomal pathway; parkinson disease; lrrk2 ... See more keywords