Dual Arginine Recognition of LRRK2 phosphorylated Rab GTPases.
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DOI: 10.1016/j.bpj.2021.03.030
Abstract: Parkinson's disease-associated LRRK2 is a multi-domain Ser/Thr kinase that phosphorylates a subset of Rab GTPases to control their effector functions. Rab GTPases are the prime regulators of membrane trafficking in eukaryotic cells. Rabs exert their… read more here.
Keywords: rab; rab gtpases; dual arginine; lrrk2 phosphorylated ... See more keywords