Articles with "lrrk2 therapeutics" as a keyword



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Pharmacodynamic Biomarkers for Emerging LRRK2 Therapeutics

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Published in 2020 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2020.00807

Abstract: Genetic studies have identified variants in the LRRK2 gene as important components of Parkinson’s disease (PD) pathobiology. Biochemical and emergent biomarker studies have coalesced around LRRK2 hyperactivation in disease. Therapeutics that diminish LRRK2 activity, either… read more here.

Keywords: pharmacodynamic biomarkers; biomarkers emerging; biomarker; lrrk2 therapeutics ... See more keywords