Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a0419-123r
Abstract: Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and… read more here.
Keywords: ricin; ricin toxin; kupffer cells; liver sinusoidal ... See more keywords
HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00769-7
Abstract: TO THE EDITOR It is believed that the inherent tolerogenic property of the liver is involved in the chronicity of hepatitis B virus (HBV) infection [1]. However, exposure to HBV in adults usually leads to… read more here.
Keywords: lsecs; hbv; cell activation; hbeag ... See more keywords
Pathological Changes in Hepatic Sinusoidal Endothelial Cells in Schistosoma japonicum-Infected Mice
Sign Up to like & getrecommendations! Published in 2023 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed8020124
Abstract: Schistosomiasis japonica is a zoonotic parasitic disease causing liver fibrosis. Liver sinusoidal endothelial cells (LSECs) exhibit fenestrations, which promote hepatocyte regeneration and reverses the process of liver fibrosis. To investigate the pathological changes of LSECs… read more here.
Keywords: sinusoidal endothelial; lsecs; infection; microscopy ... See more keywords