Involvement of fission yeast Pdc2 in RNA degradation and P-body function.
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DOI: 10.1261/rna.059766.116
Abstract: In this study we identified Pdc2, the fission yeast ortholog of human Pat1b protein, which forms a complex with Lsm1-7 and plays a role in coupling deadenylation and decapping. The involvement of Pdc2 in RNA… read more here.
Keywords: lsm1; pdc2; function; fission yeast ... See more keywords
Pat1 increases the range of decay factors and RNA bound by the Lsm1-7 complex.
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DOI: 10.1261/rna.075812.120
Abstract: Pat1 promotes the activation and assembly of multiple proteins during mRNA decay. After deadenylation, the Pat1/Lsm1-7 complex binds to transcripts containing oligo(A) tails, which can be modified by the addition of several terminal uridine residues.… read more here.
Keywords: decay factors; lsm1 complex; lsm1 binding; lsm1 ... See more keywords