LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ltbp4" as a keyword



LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts.

Sign Up to like & get
recommendations! Published in 2023 at "Circulation research"

DOI: 10.1161/circresaha.123.322494

Abstract: BACKGROUND As a part of natural disease progression, acute kidney injury (AKI) can develop into chronic kidney disease via renal fibrosis and inflammation. LTBP4 (latent transforming growth factor beta binding protein 4) regulates transforming growth… read more here.

Keywords: transforming growth; renal fibrosis; factor beta; ltbp4 ... See more keywords

Constitutional epimutations in LTBP4, a component of the TGF-β signaling, and in BRCA1, as potential drivers of early-onset colorectal cancer

Sign Up to like & get
recommendations! Published in 2025 at "Clinical Epigenetics"

DOI: 10.1186/s13148-025-01924-x

Abstract: Constitutional primary monoallelic promoter methylation of hereditary cancer genes, although rare, may explain early-onset cancers without family history. Also, promoter methylation of a hereditary cancer gene secondary to a genetic alteration in a methylation regulatory… read more here.

Keywords: cancer; methylation; crc; promoter methylation ... See more keywords

The IAAM LTBP4 Haplotype is Protective Against Dystrophin-Deficient Cardiomyopathy

Sign Up to like & get
recommendations! Published in 2024 at "Journal of Neuromuscular Diseases"

DOI: 10.3233/jnd-230129

Abstract: Background: Dilated cardiomyopathy (DCM) is a major complication of, and leading cause of mortality in Duchenne muscular dystrophy (DMD). Its severity, age at onset, and rate of progression display wide variability, whose molecular bases have… read more here.

Keywords: dystrophin deficient; iaam ltbp4; ltbp4 haplotype; haplotype protective ... See more keywords

Disruption of LTBP4 Inhibition-Induced TGFβ1 Activation Promoted Cell Proliferation and Metastasis in Skin Melanoma by Inhibiting the Activation of the Hippo-YAP1 Signaling Pathway

Sign Up to like & get
recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.673904

Abstract: Melanoma is a malignant tumor derived from melanocytes, which is the most fatal skin cancer. The present study aimed to explore and elucidate the candidate genes in melanoma and its underlying molecular mechanism. A total… read more here.

Keywords: expression; activation; ltbp4; cell ... See more keywords