Articles with "ltg" as a keyword



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Morbidity and mortality from a propensity score-matched, prospective cohort study of laparoscopic versus open total gastrectomy for gastric cancer: data from a nationwide web-based database

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Published in 2017 at "Surgical Endoscopy"

DOI: 10.1007/s00464-017-5976-0

Abstract: BackgroundControversy persists regarding the technical feasibility of laparoscopic total gastrectomy (LTG), and to our knowledge, no prospective study with a sample size sufficient to investigate its safety has been reported. We aimed to compare the… read more here.

Keywords: morbidity mortality; ltg otg; ltg; total gastrectomy ... See more keywords
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Potential advantages of robotic total gastrectomy for gastric cancer: a retrospective comparative cohort study

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Published in 2021 at "Journal of Robotic Surgery"

DOI: 10.1007/s11701-021-01328-y

Abstract: Laparoscopic total gastrectomy (LTG) is a highly technical surgery that can lead to postoperative complications. Whether the recently introduced robotic surgery overcomes the drawbacks of laparoscopic surgery in total gastrectomy remains controversial. Therefore, we aimed… read more here.

Keywords: surgery; total gastrectomy; ltg; postoperative complications ... See more keywords
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The lack of influence of IVS5-91 G>A polymorphism of the SCN1A gene on efficacy of lamotrigine in patients with focal epilepsy

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Published in 2019 at "Neurological Research"

DOI: 10.1080/01616412.2019.1635321

Abstract: ABSTRACT Background: IVS5-91G>A (rs3812718) polymorphism of the sodium voltage-gated channel alpha subunit 1 (SCN1A) gene has been associated with inadequate responsiveness to common antiepileptic drugs which act as sodium channel blockers. This study was performed… read more here.

Keywords: focal epilepsy; ltg; efficacy; scn1a gene ... See more keywords
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Docosahexaenoic acid prevents resistance to antiepileptic drugs in two animal models of drug-resistant epilepsy

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Published in 2018 at "Nutritional Neuroscience"

DOI: 10.1080/1028415x.2017.1422903

Abstract: Objectives: One-third of epileptic patients are resistant to antiepileptic drugs. Few clinical studies with small sample size indicate that polyunsaturated fatty acids could control drug-resistant epilepsy. We examined the efficacy of acute and chronic administration… read more here.

Keywords: ltg; kindled rats; drug resistant; dha ... See more keywords
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Cubosome-based thermosensitive in situ gelling system for intranasal administration of lamotrigine with enhanced antiepileptic efficacy.

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Published in 2023 at "Pharmaceutical development and technology"

DOI: 10.1080/10837450.2023.2216755

Abstract: Lamotrigine (LTG) is a second-generation antiepileptic drug that belongs to Biopharmaceutics Classification System (BCS) class II. LTG has a low probability of crossing the BBB if administered orally. This study was designed to fabricate LTG… read more here.

Keywords: ltg; drug; thermosensitive situ; antiepileptic efficacy ... See more keywords
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Lamotrigine-induced mania: warning report for the identification of vulnerable populations and expert clinical recommendations for prescription.

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Published in 2022 at "International clinical psychopharmacology"

DOI: 10.1097/yic.0000000000000390

Abstract: Lamotrigine (LTG) is an anticonvulsant drug used for the prevention of depressive episodes in bipolar disorder (BD) that might induce manic episodes in some cases. A 38-year-old man, stabilized with asenapine due to a brief… read more here.

Keywords: lamotrigine induced; ltg; manic episode; induced mania ... See more keywords
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Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment

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Published in 2022 at "Journal of Pharmacology and Pharmacotherapeutics"

DOI: 10.1177/0976500x221111455

Abstract: Objectives To build a lamotrigine (LTG) physiologically based pharmacokinetic (PBPK) model (LTG PBPK) and compare it to the clinical data from South Asian Indian patients and use this model to understand the drug interactions of… read more here.

Keywords: based pharmacokinetic; drug interactions; ltg; physiologically based ... See more keywords
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Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products

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Published in 2022 at "eLife"

DOI: 10.7554/elife.73178

Abstract: The peptidoglycan cell wall is a predominant structure of bacteria, determining cell shape and supporting survival in diverse conditions. Peptidoglycan is dynamic and requires regulated synthesis of new material, remodeling, and turnover – or autolysis… read more here.

Keywords: turnover; lytic transglycosylases; ltg; cell wall ... See more keywords