Oscillatory shear potentiates latent TGF-β1 activation more than steady shear as demonstrated by a novel force generator
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DOI: 10.1038/s41598-019-42302-x
Abstract: Cardiovascular mechanical stresses trigger physiological and pathological cellular reactions including secretion of Transforming Growth Factor β1 ubiquitously in a latent form (LTGF-β1). While complex shear stresses can activate LTGF-β1, the mechanisms underlying LTGF-β1 activation remain… read more here.
Keywords: activation; ltgf activation; steady shear; oscillatory shear ... See more keywords