Phase 1 trial of intrapleural LTI-01; single chain urokinase in complicated parapneumonic effusions or empyema.
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DOI: 10.1172/jci.insight.127470
Abstract: BACKGROUND Current dosing of intrapleural fibrinolytic therapy (IPFT) in adults with complicated parapneumonic effusion (CPE) / empyema is empiric, as dose-escalation trials have not previously been conducted. We hypothesized that LTI-01 (scuPA), which is relatively… read more here.
Keywords: trial; lti ipft; complicated parapneumonic; well tolerated ... See more keywords