Priming of LTP in amygdala and hippocampus by prior paired pulse facilitation paradigm in mice lacking brain serotonin
Sign Up to like & getrecommendations! Published in 2019 at "Hippocampus"
DOI: 10.1002/hipo.23055
Abstract: This study focuses on analyzing long‐term potentiation (LTP) changes in the lateral nucleus of the amygdala (LA) and in the CA1 region of the hippocampus in slices derived from mice deficient in tryptophan hydroxylase 2… read more here.
Keywords: ltp; hippocampus; paired pulse; mice ... See more keywords
Long-term potentiation enhancing effect of epileptic insult in the CA1 area is dependent on prior-application of primed-burst stimulation
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Brain Research"
DOI: 10.1007/s00221-020-05766-2
Abstract: Herein field recordings were utilized to test the effects of a transient period of pentylenetetrazol (PTZ) treatment on theta-burst long-term potentiation (LTP) at the Schaffer collateral-CA1 synapses as well as RT-PCR was used to investigate… read more here.
Keywords: long term; ltp; treatment; term potentiation ... See more keywords
Proteolytic Degradation of Hippocampal STEP61 in LTP and Learning
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1170-1
Abstract: Striatal-enriched protein tyrosine phosphatase (STEP) modulates key signaling molecules involved in synaptic plasticity and neuronal function. It is postulated that STEP opposes the development of long-term potentiation (LTP) and that it exerts a restraint on… read more here.
Keywords: proteolytic degradation; ltp; degradation; step61 ... See more keywords
Simultaneous Live Imaging of Multiple Endogenous Proteins Reveals a Mechanism for Alzheimer's-Related Plasticity Impairment.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.03.041
Abstract: CaMKIIα is a central mediator of bidirectional synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). To study how CaMKIIα movement during plasticity is affected by soluble amyloid-β peptide oligomers (Aβ), we used FingR… read more here.
Keywords: ltp; camkii movement; impairment; camkii ... See more keywords
Activation of liver x receptors prevents the spinal LTP induced by skin/muscle retraction in the thigh via SIRT1/NF-Κb pathway
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2019.04.002
Abstract: It has been reported that skin/muscle incision and retraction (SMIR) in the thigh, produces mechanical allodynia in the hind paw, far from the site of incision/retraction. The mechanical allodynia lasts about 22 days, indicating chronic… read more here.
Keywords: ltp; retraction; skin muscle; liver receptors ... See more keywords
Delayed effects of combined stress and Aβ infusion on L-LTP of the dentate gyrus: Prevention by nicotine
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.05.038
Abstract: Alzheimer's Disease (AD) is a progressive dementia hallmarked by the presence in the brain of extracellular beta-amyloid (Aβ) plaques and intraneuronal fibrillary tangles. Chronic stress is associated with heightened Aβ buildup and acceleration of development… read more here.
Keywords: ltp; chronic stress; area; effect ... See more keywords
LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.07.028
Abstract: Excitatory hilar mossy cells (MCs) in the dentate gyrus receive inputs from dentate granule cells (GCs) and project back to GCs locally, contralaterally, and along the longitudinal axis of the hippocampus, thereby establishing an associative… read more here.
Keywords: ltp; dentate granule; dentate gyrus; inhibition ... See more keywords
Enhanced LTP in aged rats: Detrimental or compensatory?
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2016.11.017
Abstract: ABSTRACT Age‐dependent memory deterioration has been well documented and yet an increase in rat hippocampal LTP upon aging has been reported. This poses the question of whether the enhanced LTP is a cause or an… read more here.
Keywords: aged rats; ltp; aged animals; compensatory ... See more keywords
LTP suppression by protein synthesis inhibitors is NO-dependent
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.12.009
Abstract: ABSTRACT For several decades, the ability of protein synthesis inhibitors (PSI) to suppress the long‐term potentiation (LTP) of hippocampal responses is known. It is considered that mechanisms of such impairment are related to a cessation… read more here.
Keywords: ltp; protein synthesis; synthesis inhibitors; ltp suppression ... See more keywords
β-adrenergic receptors reduce the threshold for induction and stabilization of LTP and enhance its magnitude via multiple mechanisms in the ventral but not the dorsal hippocampus
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Learning and Memory"
DOI: 10.1016/j.nlm.2018.04.010
Abstract: Graphical abstract Figure. No caption available. Highlights&bgr;‐adrenergic receptors (&bgr;‐ARs) modulate synaptic plasticity and emotional memory.LTP was induced at dorsal and ventral hippocampal slices (DH‐VH) by theta‐bursts.We found that the &bgr;‐AR modulation of LTP is strikingly… read more here.
Keywords: ltp; bgr; hippocampus; bgr ars ... See more keywords
Recombinant production and α-amylase inhibitory activity of the lipid transfer protein from Vigna unguiculata (L. Walp.) seeds
Sign Up to like & getrecommendations! Published in 2017 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2017.10.018
Abstract: Abstract Lipid transfer proteins (LTPs) are soluble plant peptides endowed with biological activities applicable in agronomy, industry, and medicine. We assessed in this work the inhibition of human and intestinal insect α-amylases by rVu-LTP. The… read more here.
Keywords: medicine; ltp; rvu ltp; lipid transfer ... See more keywords