Neutrophils Recruited by NKX2‐1 Suppression via Activation of CXCLs/CXCR2 Axis Promote Lung Adenocarcinoma Progression
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202400370
Abstract: NK2 Homeobox 1 (NKX2‐1) is a well‐characterized pathological marker that delineates lung adenocarcinoma (LUAD) progression. The advancement of LUAD is influenced by the immune tumor microenvironment through paracrine signaling. However, the involvement of NKX2‐1 in… read more here.
Keywords: lung adenocarcinoma; activation cxcls; luad; cxcls cxcr2 ... See more keywords
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer communications"
DOI: 10.1002/cac2.12275
Abstract: BACKGROUND Resistance to ferroptosis, a regulated cell death caused by iron-dependent excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma (LUAD). Intracellular antioxidant systems are required for protection against ferroptosis. The purpose… read more here.
Keywords: lung; ferroptosis; luad; cell ... See more keywords
Aberrant CpG‐methylation affects genes expression predicting survival in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1834
Abstract: Lung adenocarcinoma (LUAD) is a common diagnosed disease with high‐mortality rate, and its prognostic implications are under discovered. DNA methylation aberrations are not only an important event for dysregulation of gene expression during tumorigenesis but… read more here.
Keywords: lung adenocarcinoma; methylation; expression; luad ... See more keywords
ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6044
Abstract: BACKGROUND Lung adenocarcinoma (LUAD) is a common subtype of non-small cell lung cancer with high morbidity and mortality rates and is usually detected at advanced stages because of the early onset of metastasis. Adenosine deaminase… read more here.
Keywords: lung adenocarcinoma; luad; immune infiltration; expression ... See more keywords
APOA1 as a Potential Therapeutic Target and Novel Biomarker in Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.70142
Abstract: Apolipoprotein A1 (APOA1), the main structural protein of high‐density lipoprotein, has been implicated in cancer, but its role in lung adenocarcinoma (LUAD) remains unclear. Here, we integrate pan‐cancer and LUAD‐focused multi‐omics with patient‐serum validation, in‐vitro… read more here.
Keywords: lung; lung adenocarcinoma; immune infiltration; apoa1 potential ... See more keywords
Flavoxanthin Binds to AGR2 to Mediate Fatty Acid Oxidation and Reinforce Anoikis in Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development Research"
DOI: 10.1002/ddr.70129
Abstract: Traditional Chinese medicine (TCM) can not only alleviate symptoms in cancer patients and improve their life quality but also serve as an adjuvant therapy to reduce the toxic side effects of chemotherapy and radiotherapy, making… read more here.
Keywords: acid oxidation; agr2; luad; medicine ... See more keywords
UBE2T mediates SORBS3 ubiquitination to enhance IL‐6/STAT3 signaling and promote lung adenocarcinoma progression
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23743
Abstract: UBE2T is an oncogene in varying tumors, including lung adenocarcinoma (LUAD). SORBS3 is an important signaling regulatory protein that plays a crucial role in many cancers. This study aimed to investigate whether UBE2T promoted LUAD… read more here.
Keywords: sorbs3 ubiquitination; lung adenocarcinoma; stat3 signaling; progression ... See more keywords
miR‐195‐5p inhibits cisplatin resistance in lung adenocarcinoma by regulating DNA damage via targeting E2F7
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70015
Abstract: Lung adenocarcinoma (LUAD) emerges as one of the most lethal malignant tumors worldwide. Platinum‐based combination chemotherapy remains one of the main methods for patients with advanced LUAD. Due to the resistance, the effect of this… read more here.
Keywords: dna damage; resistance; luad cells; luad ... See more keywords
MiR-96-5p is an oncogene in lung adenocarcinoma and facilitates tumor progression through ARHGAP6 downregulation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied genetics"
DOI: 10.1007/s13353-021-00652-1
Abstract: Accumulating investigations illustrated that miRNA acts as a key regulator in tumor progression, whereas regulatory role of miR-96-5p in lung adenocarcinoma (LUAD) is warranted. Thus, we sought to probe mechanism of miR-96-5p in this disease.… read more here.
Keywords: tumor progression; lung adenocarcinoma; luad; mir ... See more keywords
LncRNA MAFG-AS1 boosts the proliferation of lung adenocarcinoma cells via regulating miR-744-5p/MAFG axis.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172465
Abstract: Lung adenocarcinoma (LUAD) is typically featured by a low 5-year survival rate, hence there is a necessary to investigate new biomarkers in LUAD progression. Competing endogenous RNA (ceRNA) network has been widely reported in the… read more here.
Keywords: lung adenocarcinoma; mir 744; luad; proliferation ... See more keywords
Extracellular vesicles promotes liver metastasis of lung cancer by ALAHM increasing hepatocellular secretion of HGF
Sign Up to like & getrecommendations! Published in 2022 at "iScience"
DOI: 10.1016/j.isci.2022.103984
Abstract: Summary Tumor-derived extracellular vesicles (EVs) are involved in tumor metastasis. Highly enriched lncRNA-ALAHM was identified from serum EVs of lung adenocarcinoma (LUAD) patients with liver metastasis by high-throughput sequencing. A mouse model of in situ… read more here.
Keywords: lung; luad; alahm; hgf ... See more keywords