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   Articles with "luad patients" as a keyword



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Identification of the susceptibility genes for COVID-19 in lung adenocarcinoma with global data and biological computation methods

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recommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"

DOI: 10.1016/j.csbj.2021.11.026

Abstract: Introduction The risk of infection with COVID-19 is high in lung adenocarcinoma (LUAD) patients, and there is a dearth of studies on the molecular mechanism underlying the high susceptibility of LUAD patients to COVID-19 from… read more here.

Keywords: susceptibility genes; susceptibility; genes covid; luad patients ... See more keywords

Integrative analysis of genomic sequencing data reveals higher prevalence of LRP1B mutations in lung adenocarcinoma patients with COPD

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-02405-9

Abstract: Both chronic Obstruction Pulmonary Disease (COPD) and lung cancer are leading causes of death globally. Although COPD and lung cancer coexist frequently, it is unknown whether lung cancer patients with COPD harbor distinct genomic characteristics… read more here.

Keywords: lrp1b; patients copd; sequencing data; analysis ... See more keywords

LEF1 is associated with immunosuppressive microenvironment of patients with lung adenocarcinoma

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recommendations! Published in 2024 at "Medicine"

DOI: 10.1097/md.0000000000039892

Abstract: Wnt/β-Catenin pathway plays an important role in the occurrence and progression of malignant tumors, especially PD-L1-mediated tumor immune evasion. However, the role of TCF/LEF, an important member of the Wnt/β-catenin pathway, in the tumor immunosuppressive… read more here.

Keywords: immunosuppressive microenvironment; tumor; luad patients; associated immunosuppressive ... See more keywords

Bioinformatics Analysis of Prognostic Significance and Immune Characteristics of CXC Chemokine Family in Patients with Lung Adenocarcinoma

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recommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/3918926

Abstract: Objective To screen CXC chemokines related to the risk of lung adenocarcinoma (LUAD) using bioinformatics and construct a CXC-based prognostic risk model to improve the diagnosis and treatment of LUAD patients. Methods The Cancer Genome… read more here.

Keywords: cxcl13; luad patients; luad; risk ... See more keywords

Downregulation of hsa-miR-30b-3p Inhibits the Oncogenicity of Lung Adenocarcinoma by Targeting the METTL7B Gene

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recommendations! Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/6883140

Abstract: Objective Lung adenocarcinoma (LUAD) is one of the malignant tumors with the highest morbidity and mortality rates worldwide. Although surgery-based combination therapy can greatly improve the prognosis of LUAD patients, the overall outcome is still… read more here.

Keywords: luad patients; lung adenocarcinoma; mettl7b gene; lung ... See more keywords

CT texture features of lung adenocarcinoma with HER2 mutation

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recommendations! Published in 2025 at "BMC Cancer"

DOI: 10.1186/s12885-025-13686-z

Abstract: Mutations in human receptor tyrosine kinase epidermal growth factor receptor-2 (HER2) are rare. This study aimed to investigate the clinical characteristics and computed tomography (CT) texture features of lung adenocarcinoma (LUAD) patients with HER2 mutation.… read more here.

Keywords: her2; luad patients; her2 mutation; luad her2 ... See more keywords

A new prognostic model for RHOV, ABCC2, and CYP4B1 to predict the prognosis and association with immune infiltration of lung adenocarcinoma

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recommendations! Published in 2023 at "Journal of Thoracic Disease"

DOI: 10.21037/jtd-23-265

Abstract: Background Lymph node metastasis is one of the important factors affecting the prognosis of lung adenocarcinoma (LUAD) patients. The key molecules in lymph node metastasis have not yet been fully revealed. Therefore, we aimed to… read more here.

Keywords: luad patients; abcc2 cyp4b1; prognosis; prognostic model ... See more keywords

Depicting growth characteristics with computed tomography for KRAS-mutated lung adenocarcinoma

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recommendations! Published in 2025 at "Quantitative Imaging in Medicine and Surgery"

DOI: 10.21037/qims-24-1880

Abstract: Background Kirsten rat sarcoma viral oncogene homolog (KRAS) is a key oncogenic driver in lung adenocarcinoma (LUAD). The correlation between KRAS mutations and the computed tomographic (CT) texture features in LUAD patients is not well… read more here.

Keywords: texture; lung adenocarcinoma; luad patients; kras mutations ... See more keywords

LRP1B mutation is associated with tumor immune microenvironment and progression-free survival in lung adenocarcinoma treated with immune checkpoint inhibitors

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recommendations! Published in 2023 at "Translational Lung Cancer Research"

DOI: 10.21037/tlcr-23-39

Abstract: Background Only a fraction of lung adenocarcinoma (LUAD) patients are eligible for immunotherapy. The identification of biomarkers for immunotherapy is crucial to improve patient outcomes. This study aims to systemically analyze LRP1B mutation and its… read more here.

Keywords: lrp1b mutation; lrp1b mutated; luad patients; immune checkpoint ... See more keywords

A Seven-Long Non-coding RNA Signature Improves Prognosis Prediction of Lung Adenocarcinoma: An Integrated Competing Endogenous RNA Network Analysis

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recommendations! Published in 2020 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2020.625977

Abstract: Early and precise prediction is an important way to reduce the poor prognosis of lung adenocarcinoma (LUAD) patients. Nevertheless, the widely used tumor, node, and metastasis (TNM) staging system based on anatomical information only often… read more here.

Keywords: network; prognosis; luad patients; signature ... See more keywords

Construction of a Novel Prognostic Signature in Lung Adenocarcinoma Based on Necroptosis-Related lncRNAs

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recommendations! Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.833362

Abstract: Background: Long non-coding RNAs (lncRNAs) are drawing increasing attention as promising predictors of prognosis for lung adenocarcinoma (LUAD) patients. Necroptosis, a novel regulated mechanism of necrotic cell death, plays an important role in the biological… read more here.

Keywords: necroptosis related; luad patients; lung adenocarcinoma; signature ... See more keywords