Pharmacokinetic comparison of nine bioactive components in rat plasma following oral administration of raw and wine-processed Ligustri Lucidi Fructus by ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000625
Abstract: An accurate and sensitive ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry method was established and validated for the determination of 9 bioactive compounds of Ligustri Lucidi Fructus in rat plasma. Separation was performed… read more here.
Keywords: lucidi fructus; high performance; ligustri lucidi; ultra high ... See more keywords
Systematically characterize the absorbed components of Ligustri Lucidi Fructus and their metabolic pathways in rat plasma by ultra-high-performance liquid chromatography-Q-Exactive Orbitrap tandem mass spectrometry combined with network pharmacology.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100484
Abstract: Ligustri Lucidi Fructus is dried and mature fruit of Ligubtrum lucidum Ait., which has the effects of nourishing liver and kidney. Herein, an accurate and sensitive method was established for separation and identification of the… read more here.
Keywords: pharmacology; network pharmacology; ligustri lucidi; lucidi fructus ... See more keywords
Study on the synergistic and attenuating mechanism of the combination of Epimedium and Ligustri lucidi fructus based on pharmacokinetics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200336
Abstract: Epimedium has a wide range of clinical applications; however, there have been numerous reports of adverse reactions in recent years, which has resulted in it being changed from a widely recognized "nontoxic" to a "potentially… read more here.
Keywords: lucidi fructus; epimedium ligustri; ligustri lucidi; combination epimedium ... See more keywords
Pharmacodynamics, Pharmacokinetics, and Kidney Distribution of Raw and Wine-Steamed Ligustri Lucidi Fructus Extracts in Diabetic Nephropathy Rats
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28020791
Abstract: The purpose of this study was to investigate differences in the pharmacodynamic, pharmacokinetic, and kidney distribution between Ligustri Lucidi Fructus (LLF) and wine-steamed Ligustri Lucidi Fructus (WLL) extracts in diabetic nephropathy (DN) rats. The DN… read more here.
Keywords: kidney distribution; lucidi fructus; wll extracts; ligustri lucidi ... See more keywords