The importance of level stratification for quantitative MR studies of lumbar intervertebral discs: a cross-sectional analysis in 101 healthy adults
Sign Up to like & getrecommendations! Published in 2019 at "European Spine Journal"
DOI: 10.1007/s00586-019-06059-1
Abstract: To investigate whether quantitative T2-times depend on lumbar intervertebral disc (IVD) level. The lumbar spine (Th12/L1–L5/S1) of 101 participants (53.5% female, 30.0[± 3.6]years, 173.5[± 9.6]cm and 69.9[± 13.4]kg), without history of back pain, was examined on a 3T… read more here.
Keywords: pfirrmann grade; lumbar intervertebral; time; level ... See more keywords
ISSLS PRIZE IN BASIC SCIENCE 2020: Beyond microstructure—circumferential specialization within the lumbar intervertebral disc annulus extends to collagen nanostructure, with counterintuitive relationships to macroscale material properties
Sign Up to like & getrecommendations! Published in 2019 at "European Spine Journal"
DOI: 10.1007/s00586-019-06223-7
Abstract: Purpose To determine whether the annulus of lumbar intervertebral discs contains circumferential specialization in collagen nanostructure and assess whether this coincides with functional differences in macroscale material properties. Methods Anterior and posterior disc wall samples… read more here.
Keywords: collagen nanostructure; lumbar intervertebral; material properties; material ... See more keywords
Numerical study on the effect of microgravity on biomechanics in human lumbar intervertebral discs
Sign Up to like & getrecommendations! Published in 2025 at "NPJ Microgravity"
DOI: 10.1038/s41526-025-00483-y
Abstract: This study was aimed to investigate the effects of microgravity on the biochemical and biomechanical change in the lumbar intervertebral disc (IVD) using a modelling approach. The lumbar IVD was considered as an inhomogeneous, porous,… read more here.
Keywords: biomechanics; lumbar intervertebral; glucose oxygen; microgravity ... See more keywords
1,25(OH)₂D₃ inhibits ferroptosis in nucleus pulposus cells via VDR signaling to mitigate lumbar intervertebral disc degeneration
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-92405-x
Abstract: Lumbar intervertebral disc degeneration (LIDD) serves as a principal contributor to low back pain, a condition that poses considerable global health and socioeconomic challenges. Recent studies have emphasized the significance of ferroptosis, an iron-dependent mechanism… read more here.
Keywords: disc degeneration; ferroptosis; intervertebral disc; lumbar intervertebral ... See more keywords
Normalization of Spinal Cord Displacement with the Straight leg Raise and Resolution of Sciatica in Patients with Lumbar Intervertebral Disc Herniation: A 1.5-Year Follow-up Study.
Sign Up to like & getrecommendations! Published in 2019 at "Spine"
DOI: 10.1097/brs.0000000000003047
Abstract: STUDY DESIGN Controlled radiologic follow-up study. OBJECTIVE To ascertain if changes in cord excursion with SLR at 1.5-year follow-up time accompany changes in clinical symptoms SUMMARY OF BACKGROUND DATA.: Lumbar intervertebral disc herniation (LIDH) is… read more here.
Keywords: disc herniation; lumbar intervertebral; study; year follow ... See more keywords
Can TRIF/TICAM-1 Dependent Pathway be Target Pathway in Lumbar Intervertebral Disc Degeneration?
Sign Up to like & getrecommendations! Published in 2022 at "Turkish neurosurgery"
DOI: 10.2139/ssrn.4178893
Abstract: AIM The current study aims to elucidate the role of the TIR-domain-containing adaptor-inducing interferon-β (TRIF) dependent pathway in intervertebral disc degeneration (IVD). MATERIAL AND METHODS 88 adult male patients with low back pain (LBP) (+/-… read more here.
Keywords: lumbar intervertebral; disc degeneration; intervertebral disc; dependent pathway ... See more keywords
Morphology and Composition of Lumbar Intervertebral Discs: Comparative Analyses of Manual Measurement and Computer-Assisted Algorithms
Sign Up to like & getrecommendations! Published in 2024 at "Bioengineering"
DOI: 10.3390/bioengineering11050466
Abstract: Background: The morphology and internal composition, particularly the nucleus-to-cross sectional area (NP-to-CSA) ratio of the lumbar intervertebral discs (IVDs), is important information for finite element models (FEMs) of spinal loadings and biomechanical behaviors, and, yet,… read more here.
Keywords: computer; intervertebral discs; composition; assisted algorithms ... See more keywords
Evaluating Lumbar Intervertebral Disc Degeneration on a Compositional Level Using Chemical Exchange Saturation Transfer: Preliminary Results in Patients with Adolescent Idiopathic Scoliosis
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11060934
Abstract: Lumbar intervertebral disc (IVD) degeneration is characterized by structural and compositional changes. This study aimed to assess the glycosaminoglycan (GAG) content of IVDs of patients with adolescent idiopathic scoliosis (AIS) and healthy controls using GAG… read more here.
Keywords: patients adolescent; idiopathic scoliosis; lumbar intervertebral; adolescent idiopathic ... See more keywords
A narrative review of non-operative treatment, especially traditional Chinese medicine therapy, for lumbar intervertebral disc herniation.
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience trends"
DOI: 10.5582/bst.2017.01199
Abstract: Lumbar intervertebral disc herniation (LIDH), as the main contributor to low back pain and sciatica, imposes a heavy burden on both the individual and society. Non-operative treatment or conservative treatment has proven effective in alleviation… read more here.
Keywords: medicine; lumbar intervertebral; treatment; non operative ... See more keywords