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Published in 2019 at "Chromatographia"
DOI: 10.1007/s10337-019-03811-z
Abstract: Evaluating lumefantrine enantioselectivity and properly quantifying its enantiomers is essential for a deeper understanding of the impact of the enantioselectivity in the pharmacodynamic and pharmacokinetic properties of the drug. For this, a chiral chromatographic method…
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Keywords:
phase;
enantiomers tablet;
lumefantrine;
method ... See more keywords
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Published in 2021 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2021.103635
Abstract: Lumefantrine is used to treat uncomplicated malaria caused by pure or mixed Plasmodium falciparum infections and as a prophylactic against recrudescence following artemether therapy. However, the pharmaceutical is released into the aquatic environment from industrial…
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Keywords:
growth;
lumefantrine;
raphidocelis subcapitata;
chlorella vulgaris ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202082
Abstract: Background Lumefantrine is a long-acting antimalarial drug with an elimination half-life of over 3 days and protein binding of 99 percent. Correlation of lumefantrine concentrations from capillary plasma via fingerprick (Cc) versus venous plasma (Cv)…
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Keywords:
plasma;
capillary venous;
lumefantrine;
correlation lumefantrine ... See more keywords
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Published in 2023 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2023v15i3.47698
Abstract: Objective: The objective of the present study was to develop and validate a stability indicating RP-HPLC method for Lumefantrine (LF) and its organic impurities using a central composite design (CCD). Methods: A specific, simple quality…
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Keywords:
lumefantrine;
organic impurities;
stability indicating;
indicating hplc ... See more keywords
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Published in 2020 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v19i11.1
Abstract: Purpose: To develop and compare classical liposomes (CL), stealth liposomes (SL) and super-stealth liposomes (SSL) encapsulating lumefantrine for intravenous administration. Method: CL, SL or SSL were prepared by thin-layer evaporation method and evaluated for particle…
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Keywords:
stealth liposomes;
lumefantrine;
stealth;
pharmacodynamic study ... See more keywords