Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.0751
Abstract: Importance There is a clear need for a molecular subtyping approach in prostate cancer to identify clinically distinct subgroups that benefit from specific therapies. Objectives To identify prostate cancer subtypes based on luminal and basal… read more here.
Keywords: prostate; luminal basal; biology; prostate cancer ... See more keywords
Assessment of Luminal and Basal Phenotypes in Bladder Cancer
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DOI: 10.1038/s41598-020-66747-7
Abstract: Genomic profiling studies have demonstrated that bladder cancer can be divided into two molecular subtypes referred to as luminal and basal with distinct clinical behaviors and sensitivities to frontline chemotherapy. We analyzed the mRNA expressions… read more here.
Keywords: cancer; bladder cancer; luminal basal; molecular subtypes ... See more keywords
Abstract 4589: SRC drives invasion of luminal, but not basal, bladder cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-4589
Abstract: Preventing progression from non-muscle invasive to muscle invasive bladder cancer (BC) is a major clinical priority. This transition is defined by tumor invasion through the bladder epithelium basement membrane into the lamina propria and muscle… read more here.
Keywords: bladder cancer; luminal basal; src; cancer ... See more keywords
Abstract ES10-2: Understanding breast cancer using a developmental perspective
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs19-es10-2
Abstract: Parallels among embryonic development, stem cells, and cancer have long been recognized. We identified, isolated, and characterized stem cells that first become committed to a mammary fate during embryogenesis; we refer to these cells as… read more here.
Keywords: understanding breast; breast; breast cancer; luminal basal ... See more keywords
Identification and validation of immunohistochemical marker panels to predict the prognosis of muscle invasive bladder cancer
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DOI: 10.21037/tau-22-538
Abstract: Background Currently, the treatment regimen of bladder cancer depends on the stage and grade. Yet, patients with similar histopathological characteristics may have distinct prognosis. Luminal/basal subtyping had proved to be a satisfactory subtyping method. Here… read more here.
Keywords: bladder cancer; prognosis; luminal basal; method ... See more keywords
Relapse-Free Survival and PD-L1 Expression in First High- and Low-Grade Relapsed Luminal, Basal and Double-Negative P53-Mutant Non-Muscular Invasive Bladder Cancer Depending on Previous Chemo- and Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12051316
Abstract: The goal of this study was to assess how PD-L1 expression in tissue specimens of patients with main molecular subtypes of NMIBC (luminal, basal and double-negative p53-mutant) associates with relapsed-free survival in dependence on the… read more here.
Keywords: basal; bladder; double negative; luminal basal ... See more keywords