Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2017.11.016
Abstract: Summary The existence of slow-cycling luminal cells in the prostate has been suggested, but their identity and functional properties remain unknown. Using a bigenic mouse model to earmark, isolate, and characterize the quiescent stem-like cells,… read more here.
Keywords: luminal cells; progenitor cell; label retaining; castration ... See more keywords
Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00359-18
Abstract: Aging and stress promote senescence, which has intrinsic tumor suppressor functions and extrinsic tumor promoting properties. Therefore, it is of utmost importance to delineate the effects of senescence inducers on the various types of cells… read more here.
Keywords: senescent breast; luminal cells; senescence; breast luminal ... See more keywords
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2023-208835
Abstract: Aims Cytokeratin 5 (CK5) is a surrogate maker of progenitor cells and early glandular and myoepithelial cells (MECs) in the breast, and CK5 expression in breast MECs varies from ducts to lobules, and from normal… read more here.
Keywords: mecs; luminal cells; myoepithelial cells; ck5 expression ... See more keywords
Remaining Prostate Luminal Cells Regenerate after Androgen Deprivation.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2020-068
Abstract: Most prostate luminal cells that survive androgen deprivation can contribute to organ regeneration. read more here.
Keywords: prostate luminal; remaining prostate; androgen deprivation; cells regenerate ... See more keywords
Identifying luminal and basal mammary cell specific genes and their expression patterns during pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267211
Abstract: Mammary gland is present in all mammals and usually functions in producing milk to feed the young offspring. Mammogenesis refers to the growth and development of mammary gland, which begins at puberty and ends after… read more here.
Keywords: basal luminal; cell; mammary gland; luminal cells ... See more keywords
NEDD9 Overexpression Causes Hyperproliferation of Luminal Cells and Cooperates with HER2 Oncogene in Tumor Initiation: A Novel Prognostic Marker in Breast Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15041119
Abstract: Simple Summary Neural precursor cell expressed, developmentally downregulated protein 9 (NEDD9) is an adaptor protein that promotes integrin/RTK signaling. The overexpression of NEDD9 in HER2+ breast cancer correlates with reduced relapse-free survival. We generated a… read more here.
Keywords: luminal cells; nedd9 overexpression; overexpression; breast cancer ... See more keywords