Tandem repeated expression of lunasin gene in Pichia pastoris and its anti-inflammatory activity in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2018.01.013
Abstract: Lunasin is a novel promising health-beneficial peptide derived from soybean. However, the application of lunasin is limited by its high cost. In this study, we developed a successful protocol for expression of a dimer formation… read more here.
Keywords: anti inflammatory; lunasin; pichia pastoris; expression ... See more keywords
The Effect of Lunasin on Receptor Activator of Nuclear Factor Kappa‐B Ligand−mediated Osteoclast Formation from RAW 264.7 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2018.02.023
Abstract: Introduction: To date, no study has investigated the antiresorptive property of lunasin. Hence, the present study aimed to assess the ability of lunasin to inhibit the osteoclast formation using RAW 264.7 cells. We hypothesized that… read more here.
Keywords: mgr mol; osteoclast formation; lunasin; raw 264 ... See more keywords
Lunasin abrogates monocytes to endothelial cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2017.09.004
Abstract: HighlightsLunasin ameliorated adhesion of THP‐1 monocytes to HUVECs.Lunasin suppressed the expression of VCAM‐1 and E‐selectin, but not ICAM‐1.Lunasin stimulated the expression of KLF2 mediated by the MEK5/ERK5 pathway. ABSTRACT The adherence of monocytes to endothelial… read more here.
Keywords: lunasin abrogates; abrogates monocytes; lunasin; expression ... See more keywords
The potential of lunasin extract for the prevention of breast cancer progression by upregulating E-Cadherin and inhibiting ICAM-1
Sign Up to like & getrecommendations! Published in 2021 at "F1000Research"
DOI: 10.12688/f1000research.55385.1
Abstract: Background: Research in natural substances for their anticancer potential has become increasingly popular. Lunasin, a soybean protein, is known to inhibit cancer progression via various pathways. The aim of this study was to investigate the… read more here.
Keywords: lunasin extract; lunasin; expression; cancer progression ... See more keywords
Liposomes Containing Amaranth Unsaponifiable Matter and Soybean Lunasin Suppress ROS Production in Fibroblasts and Reduced Interleukin Production in Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191811678
Abstract: Inflammation is a normal response in defense to agents that may cause damage to the human body. When inflammation becomes chronic, reactive oxygen species (ROS) are produced; which could lead to diseases such as cancer.… read more here.
Keywords: production; lunasin; ros production; amaranth unsaponifiable ... See more keywords
Lunasin as a Promising Plant-Derived Peptide for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179548
Abstract: Cancer has become one of the main public health problems worldwide, demanding the development of new therapeutic agents that can help reduce mortality. Lunasin is a soybean peptide that has emerged as an attractive option… read more here.
Keywords: derived peptide; lunasin promising; promising plant; lunasin ... See more keywords
Liposomes Loaded with Amaranth Unsaponifiable Matter and Soybean Lunasin Prevented Melanoma Tumor Development Overexpressing Caspase-3 in an In Vivo Model
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102214
Abstract: The objective of this study was to assess the effectiveness of liposomes loaded with soybean lunasin and amaranth unsaponifiable matter (UM + LunLip) as a source of squalene in the prevention of melanoma skin cancer… read more here.
Keywords: soybean lunasin; lunasin; unsaponifiable matter; amaranth unsaponifiable ... See more keywords