Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202504922
Abstract: Mesenchymal stromal cells (MSC) have emerged as a promising therapeutic option for neuropathic pain (NP), but the mechanisms remain elusive. Using murine pain models, it is demonstrated that MSC effectively alleviates pain, with efficacy comparable… read more here.
Keywords: npy2r sensory; brain; lung brain; mesenchymal stromal ... See more keywords
Long-term survival after surgical resection of metachronous lung, brain and thyroid gland metastases from rectal cancer: A case report
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2021.01.054
Abstract: Highlights • Brain and thyroid metastasis of rectal cancer are uncommon, and prognosis are poor.• Lung, brain and thyroid metastasis of rectal cancer was resected metachronous.• This case survived 19 years after the initial rectal… read more here.
Keywords: brain thyroid; rectal cancer; lung brain; case ... See more keywords
The lung-brain axis: A new frontier in host-microbe interactions.
Sign Up to like & getrecommendations! Published in 2022 at "Immunity"
DOI: 10.1016/j.immuni.2022.03.015
Abstract: The gut microbiome is well-known to shape local and distal immune responses, both in health and disease. In a recent issue of Nature, Hosang et al. demonstrate how the lung microbiome regulates the magnitude of autoimmune… read more here.
Keywords: frontier host; lung brain; new frontier; axis new ... See more keywords
Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-87706-w
Abstract: Hyperoxia-induced lung injury plays a key role in the development of bronchopulmonary dysplasia (BPD), characterized by inflammatory injury and impaired lung development in preterm infants. Although BPD is a predictor of poor neurodevelopmental outcomes, currently… read more here.
Keywords: lung brain; brain; evs; brain injury ... See more keywords
Lung brain metastasis pseudoprogression after nivolumab and ipilimumab combination treatment
Sign Up to like & getrecommendations! Published in 2018 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.12873
Abstract: Immunotherapy has revolutionized the treatment of non‐small cell lung cancer; however, its role in the treatment response of lung brain metastasis is unknown. Understanding immunotherapy activity in the central nervous system is important in order… read more here.
Keywords: brain metastasis; treatment; lung brain; lung ... See more keywords
Perinatal Hyperoxia and Developmental Consequences on the Lung-Brain Axis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5784146
Abstract: Approximately 11.1% of all newborns worldwide are born preterm. Improved neonatal intensive care significantly increased survival rates over the last decades but failed to reduce the risk for the development of chronic lung disease (i.e.,… read more here.
Keywords: hyperoxia; brain axis; lung brain; brain ... See more keywords
Triangular Causality Among Pulmonary Hypertension, Sleep Disorders, and Brain Structure at the Genetic Level: A Mendelian Randomization Study Focused on the Lung-Brain Axis
Sign Up to like & getrecommendations! Published in 2025 at "Nature and Science of Sleep"
DOI: 10.2147/nss.s495071
Abstract: Background The bidirectional relationship between pulmonary hypertension (PH) and sleep disorders has attracted significant research attention. The concept of the lung-brain axis has further highlighted the need for a holistic approach to managing these diseases.… read more here.
Keywords: brain axis; sleep disorders; brain; lung brain ... See more keywords
Neuropathology and neuroinflammation in Alzheimer’s disease via bidirectional lung–brain axis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2024.1449575
Abstract: Alzheimer’s disease (AD) is the most common form of age-related dementia worldwide. Although the neuropathology of AD is clear, its pathogenesis remains unclear. Recently, conceptualising AD as brain-centred has reoriented many scientists because the close… read more here.
Keywords: alzheimer disease; brain; via bidirectional; brain axis ... See more keywords
Putative Role of the Lung–Brain Axis in the Pathogenesis of COVID-19-Associated Respiratory Failure: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030729
Abstract: The emergence of SARS-CoV-2 and its related disease caused by coronavirus (COVID-19) has posed a huge threat to the global population, with millions of deaths and the creation of enormous social and healthcare pressure. Several… read more here.
Keywords: lung brain; systematic review; brain; covid ... See more keywords
The Impact of Pulmonary Disorders on Neurological Health (Lung-Brain Axis)
Sign Up to like & getrecommendations! Published in 2024 at "Immune Network"
DOI: 10.4110/in.2024.24.e20
Abstract: The brain and lungs, vital organs in the body, play essential roles in maintaining overall well-being and survival. These organs interact through complex and sophisticated bi-directional pathways known as the 'lung–brain axis', facilitated by their… read more here.
Keywords: brain; lung; brain axis; lung brain ... See more keywords