Optimum diameter threshold for lung nodules at baseline lung cancer screening with low-dose chest CT: exploration of results from the Korean Lung Cancer Screening Project
Sign Up to like & getrecommendations! Published in 2021 at "European Radiology"
DOI: 10.1007/s00330-021-07827-8
Abstract: To explore the optimum diameter threshold for solid nodules to define positive results at baseline screening low-dose CT (LDCT) and to compare two-dimensional and volumetric measurement of lung nodules for the diagnosis of lung cancers.… read more here.
Keywords: lung cancer; diameter threshold; lung cancers; diameter ... See more keywords
Using Bayesian networks for environmental health risk assessment.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental research"
DOI: 10.1016/j.envres.2021.112059
Abstract: The study investigated the potential relationships between air pollution, socio-economy, and proven pathologies (e.g., respiratory, cardiovascular) within an industrial area in Southern France (Etang de Berre), gathering steel industries, oil refineries, shipping, road traffic and… read more here.
Keywords: networks environmental; years old; bayesian networks; using bayesian ... See more keywords
Lung cancers associated with cystic airspaces: CT features and pathologic correlation.
Sign Up to like & getrecommendations! Published in 2019 at "Lung cancer"
DOI: 10.1016/j.lungcan.2019.05.012
Abstract: OBJECTIVE Lung cancer associated with cystic airspaces (LCCA) is a rare entity. The diagnosis and treatment is often delayed due to lack of comprehension of this disease. We aimed to elucidate LCCA's clinicopathological characteristics and… read more here.
Keywords: lung; associated cystic; cancers associated; cystic airspaces ... See more keywords
Tumor microenvironment disparity in multiple primary lung cancers: Impact of non-intrinsic factors, histological subtypes, and genetic aberrations
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101102
Abstract: Highlights • Tumor microenvironment (TME) was compared among multiple primary lung cancers (MPLCs).• Sex and smoking status concomitantly impacted PD-L1 expression in paired tumors.• EGFR mutations were independently associated with PD-L1 expression.• KRAS mutations altered… read more here.
Keywords: primary lung; multiple primary; histological subtypes; tumor microenvironment ... See more keywords
The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-27341-1
Abstract: Histology plays an essential role in therapeutic decision-making for lung cancer patients. However, the molecular determinants of lung cancer histology are largely unknown. We conduct whole-exome sequencing and microarray profiling on 19 micro-dissected tumor regions… read more here.
Keywords: lung; different histologic; histology; lung cancers ... See more keywords
A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29905-1
Abstract: Targeting ferroptosis, a unique cell death modality triggered by unrestricted lipid peroxidation, in cancer therapy is hindered by our incomplete understanding of ferroptosis mechanisms under specific cancer genetic contexts. KEAP1 (kelch-like ECH associated protein 1)… read more here.
Keywords: lung; coq fsp1; ferroptosis; lung cancers ... See more keywords
miR-1297 Promotes Cell Proliferation of Non-Small Cell Lung Cancer Cells: Involving in PTEN/Akt/Skp2 Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2017.3886
Abstract: Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a lipid and protein phosphatase and possesses an antitumor effect in lung cancers. miRNAs are reportedly abnormally expressed in human lung cancers. However, whether miRNA… read more here.
Keywords: skp2; mir 1297; expression; cell ... See more keywords
The role of tumour neoantigens in the differential response to immunotherapy (IO) in EGFR and BRAF mutated lung cancers: Quantity or quality?
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz253.084
Abstract: Abstract Background Lung cancer patients with activating EGFR mutations tend to respond poorly to IO, but this is not true for all activating mutation driven lung cancers. Recent data show that patients with BRAF mutations… read more here.
Keywords: neoantigen; egfr; braf; advisory consultancy ... See more keywords
The future burden of lung cancer attributable to current modifiable behaviours: a pooled study of seven Australian cohorts.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of epidemiology"
DOI: 10.1093/ije/dyy136
Abstract: Background Knowledge of preventable disease and differences in disease burden can inform public health action to improve health and health equity. We quantified the future lung cancer burden preventable by behavioural modifications across Australia. Methods… read more here.
Keywords: seven australian; burden; lung cancer; lung cancers ... See more keywords
Predicting Lung Cancers Using Epidemiological Data: A Generative-Discriminative Framework
Sign Up to like & getrecommendations! Published in 2021 at "IEEE/CAA Journal of Automatica Sinica"
DOI: 10.1109/jas.2021.1003910
Abstract: Predictive models for assessing the risk of developing lung cancers can help identify high-risk individuals with the aim of recommending further screening and early intervention. To facilitate pre-hospital self-assessments, some studies have exploited predictive models… read more here.
Keywords: generative discriminative; predicting lung; lung; discriminative framework ... See more keywords
Evaluating Histological Subtypes Classification of Primary Lung Cancers on Unenhanced Computed Tomography Based on Random Forest Model
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Healthcare Engineering"
DOI: 10.1155/2023/8964676
Abstract: Lung cancer is the leading cause of cancer-related death in many countries, and an accurate histopathological diagnosis is of great importance in subsequent treatment. The aim of this study was to establish the random forest… read more here.
Keywords: primary lung; classification; sclc; lung ... See more keywords