Diosgenin promotes cisplatin‐induced apoptosis through oxidative DNA damage in A549 non‐small cell lung cells
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11862
Abstract: The efficacy of cisplatin‐based chemotherapy in malignancy is limited by the occurrence of innate and acquired drug resistance. Clinical observations suggest that targeting phytopharmaceuticals is the right choice to enhance the effectiveness of conventional chemotherapy.… read more here.
Keywords: a549 non; apoptosis; non small; small cell ... See more keywords
Allelic imbalance of HLA-B expression in human lung cells infected with coronavirus and other respiratory viruses
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-022-01070-5
Abstract: The human leucocyte antigen (HLA) loci have been widely characterized to be associated with viral infectious diseases using either HLA allele frequency-based association or in silico predicted studies. However, there is less experimental evidence to… read more here.
Keywords: hla; human lung; lung cells; expression ... See more keywords
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2575-3
Abstract: The coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with more than 780,000 deaths worldwide (as of 20 August 2020). To develop antiviral interventions… read more here.
Keywords: lung cells; infection; human lung; chloroquine ... See more keywords
Repeated infections of dengue (serotype DENV-2) in lung cells of BALB/c mice lead to severe histopathological consequences
Sign Up to like & getrecommendations! Published in 2018 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2018.1492765
Abstract: ABSTRACT To determine the effect of DENV (serotype 2) repeated infections on lung cells is the main goal of this study. From the result, lung histology of control BALB/c mice showed normal alveolar morphology, while… read more here.
Keywords: lung cells; denv; repeated infections; severe histopathological ... See more keywords
P51 Lung epithelial cell inhibition of cytokine production by peripheral blood mononuclear cells and lung lymphocytes
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DOI: 10.1136/thoraxjnl-2017-210983.193
Abstract: Introduction Type 2 cytokines such as IL-5, IL-13 and IL-4 produced by primed type 2 T cells have been shown to be important in the pathogenesis of eosinophilic airway inflammation. Factors regulating the state of activation… read more here.
Keywords: lung cells; epithelial cells; cytokine; pbmc ... See more keywords
LiCoO2 particles used in Li-ion batteries induce primary mutagenicity in lung cells via their capacity to generate hydroxyl radicals
Sign Up to like & getrecommendations! Published in 2020 at "Particle and Fibre Toxicology"
DOI: 10.1186/s12989-020-0338-9
Abstract: Li-ion batteries (LIB) are used in most portable electronics. Among a wide variety of materials, LiCoO2 (LCO) is one of the most used for the cathode of LIB. LCO particles induce oxidative stress in mouse… read more here.
Keywords: lung cells; particles used; ion batteries; lco particles ... See more keywords
Profiling Distinctive Inflammatory and Redox Responses to Hydrogen Sulfide in Stretched and Stimulated Lung Cells
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DOI: 10.3390/antiox11051001
Abstract: Hydrogen sulfide (H2S) protects against stretch-induced lung injury. However, the impact of H2S on individual cells or their crosstalk upon stretch remains unclear. Therefore, we addressed this issue in vitro using relevant lung cells. We… read more here.
Keywords: lung cells; inflammatory; release; hydrogen sulfide ... See more keywords
Polyphosphate Reverses the Toxicity of the Quasi-Enzyme Bleomycin on Alveolar Endothelial Lung Cells In Vitro †
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13040750
Abstract: Simple Summary Bleomycin (BLM) is a medication introduced used to treat various types of cancer, including testicular cancer, ovarian cancer, and Hodgkin’s disease. Its most serious side effect is pulmonary fibrosis and impaired lung function.… read more here.
Keywords: polyp; lung cells; bleomycin; toxicity ... See more keywords
Fetal Lung Cells Transfer Improves Emphysematous Change in a Mouse Model of Neutrophil Elastase-Induced Lung Emphysema
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DOI: 10.3390/cimb44090269
Abstract: Recently, several studies for lung regeneration have been reported. However, regenerating the lung tissue by the transfer of any cells directly to the lung has been hardly successful. The aim of this study was to… read more here.
Keywords: transfer; lung emphysema; lung; lung cells ... See more keywords
Antifibrotic and Regenerative Effects of Treamid in Pulmonary Fibrosis
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DOI: 10.3390/ijms21218380
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease characterized by interstitial fibrosis and progressive respiratory failure. Pirfenidone and nintedanib slow down but do not stop the progression of IPF. Thus, new compounds with high… read more here.
Keywords: lung cells; fibrosis; antifibrotic regenerative; pulmonary fibrosis ... See more keywords
Evaluation of the Toxicity on Lung Cells of By-Products Present in Naphthalene Secondary Organic Aerosols
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11040319
Abstract: In 2018, seven million people died prematurely due to exposure to pollution. Polycyclic aromatic hydrocarbons (PAHs) are a significant source of secondary organic aerosol (SOA) in urban areas. We investigated the toxic effects of by-products… read more here.
Keywords: lung cells; secondary organic; evaluation toxicity; cells products ... See more keywords