Expression of heme oxygenase-1 in type II pneumocytes protects against heatstroke-induced lung damage
Sign Up to like & getrecommendations! Published in 2020 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-020-01152-7
Abstract: Heatstroke (HS) is an acute clinical disease characterized by abnormal hyperthermia and multi-organ dysfunction. Heme oxygenase (HO)-1, also called heat shock protein (HSP)32, is induced by hyperthermia and also plays protective roles in many lung… read more here.
Keywords: heat; induced lung; heme oxygenase; damage ... See more keywords
Amifostine analog, DRDE-30, alleviates radiation induced lung damage by attenuating inflammation and fibrosis.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120518
Abstract: BACKGROUND Radiotherapy of thoracic neoplasms and accidental radiation exposure often results in pneumonitis and fibrosis of lungs. Here, we investigated the potential of amifostine analogs: DRDE-07, DRDE-30, and DRDE-35, in alleviating radiation-induced lung damage. METHODS… read more here.
Keywords: lung damage; radiation; induced lung; drde drde ... See more keywords
Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00488-5
Abstract: Treatment of severe Coronavirus Disease 2019 (COVID-19) is challenging. We performed a phase 2 trial to assess the efficacy and safety of human umbilical cord-mesenchymal stem cells (UC-MSCs) to treat severe COVID-19 patients with lung… read more here.
Keywords: covid patients; trial; lung damage; covid ... See more keywords
A particle of concern: explored and proposed underlying mechanisms of microplastic-induced lung damage and pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2025 at "Inhalation Toxicology"
DOI: 10.1080/08958378.2025.2461048
Abstract: Abstract Purpose In the past decade, microplastics (MPs) have drawn significant attention as widespread environmental contaminants, with research increasingly highlighting their harmful effects on respiratory health in aquatic and terrestrial organisms. Findings revealed microplastics in… read more here.
Keywords: lung damage; pulmonary fibrosis; fibrosis; microplastic induced ... See more keywords
A multichannel feature-based approach for longitudinal lung CT registration in the presence of radiation induced lung damage
Sign Up to like & getrecommendations! Published in 2021 at "Physics in Medicine and Biology"
DOI: 10.1088/1361-6560/ac1b1d
Abstract: Quantifying parenchymal tissue changes in the lungs is imperative in furthering the study of radiation induced lung damage (RILD). Registering lung images from different time-points is a key step of this process. Traditional intensity-based registration… read more here.
Keywords: radiation induced; induced lung; registration; lung damage ... See more keywords
313. Host Protein Biomarkers Predicting Severity of Lung Damage due to COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab466.515
Abstract: Abstract Background Biomarkers to predict the severity of lung damage due to COVID-19 are urgently needed to inform management and treatment decisions. Our objective was to investigate the predictive value of host proteins for worsening… read more here.
Keywords: icu; covid; host; lung damage ... See more keywords
143: Lung Transplantation for Severe Lung Damage in Patients With End-Stage COVID-19: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000726460.44216.82
Abstract: INTRODUCTION: In the current COVID-19 pandemic, no proven effective treatment is available Critical patients with COVID-19, have been noted to progress to irreversible fatal respiratory failure Lung transplantation could be a life-saving procedure for COVID-19… read more here.
Keywords: lung damage; lung transplantation; lung transplant; end stage ... See more keywords
DYNAMICS OF ECHOCARDIOGRAPHY CHARACTERISTICS OF THE MYOCARDIUM IN PATIENTS WITH CONFIRMED DIAGNOSIS OF COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837100.71806.55
Abstract: Objective: It has now been shown that the SARS-Cov2 virus can be found in myocardial tissue. It is still unknown whether persistence of the virus in cardiomyocytes always leads to clinically significant heart damage. The… read more here.
Keywords: dynamics echocardiography; echocardiography characteristics; covid; lung damage ... See more keywords
Divergent Effects of Neutrophils on Fas-Induced Pulmonary Inflammation, Apoptosis, and Lung Damage
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DOI: 10.1097/shk.0000000000000685
Abstract: ABSTRACT Pulmonary Fas activation is essential in the pathogenesis of the acute respiratory distress syndrome. It remains unclear whether Fas-induced lung injury is dependent on neutrophils or mainly triggered by epithelial cell apoptosis. The contribution… read more here.
Keywords: fas; apoptosis; fas induced; lung damage ... See more keywords
Acute Over-Ventilation Does Not Cause Lung Damage in Moderately Hemorrhaged Swine.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.01048.2020
Abstract: Airway management is important in trauma and critically ill patients. Prolonged mechanical ventilation results in over-ventilation induced lung barotrauma, but few studies have examined the consequence of acute (1 h or less) over-ventilation. We hypothesized… read more here.
Keywords: cause lung; volume; ventilation; damage ... See more keywords
Surfactant-derived protein type B: a new biomarker linked to respiratory failure and lung damage in mild to moderate SARS-CoV-2 pneumonia
Sign Up to like & getrecommendations! Published in 2024 at "ERJ Open Research"
DOI: 10.1183/23120541.00301-2024
Abstract: Background The COVID-19 pandemic has led to significant concern due to its impact on human health, particularly through pneumonia-induced lung damage. Surfactant proteins A and D (SP-A and SP-D) are implicated in COVID-19 lung damage,… read more here.
Keywords: lung damage; covid; biomarker; pneumonia ... See more keywords