The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.127647
Abstract: Oxidative stress is a major contributor to chronic lung diseases. Antioxidants such as N-acetylcysteine (NAC) are broadly viewed as protective molecules that prevent the mutagenic effects of reactive oxygen species. Antioxidants may, however, increase the… read more here.
Keywords: lung adenocarcinoma; lung emphysema; lung; mice ... See more keywords
Fetal Lung Cells Transfer Improves Emphysematous Change in a Mouse Model of Neutrophil Elastase-Induced Lung Emphysema
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DOI: 10.3390/cimb44090269
Abstract: Recently, several studies for lung regeneration have been reported. However, regenerating the lung tissue by the transfer of any cells directly to the lung has been hardly successful. The aim of this study was to… read more here.
Keywords: transfer; lung emphysema; lung; lung cells ... See more keywords