Dichotomous role of integrin‐β5 in lung endothelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12156
Abstract: Abstract Pulmonary arterial hypertension (PAH) is a progressive, devastating disease, and its main histological manifestation is an occlusive pulmonary arteriopathy. One important functional component of PAH is aberrant endothelial cell (EC) function including apoptosis‐resistance, unchecked… read more here.
Keywords: integrin; role integrin; lung endothelial; expression ... See more keywords
Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.201812-2311oc
Abstract: RATIONALE The loss of pulmonary endothelial cells in emphysema is associated with increased lung ceramide. Ceramide perturbations may cause adaptive alterations in other bioactive sphingolipids, with pathogenic implications. We reported a negative correlation between emphysema… read more here.
Keywords: role; gcs; lung; lung endothelial ... See more keywords
Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0373oc
Abstract: Endothelial dysfunction and inflammation contribute to the vascular pathology of Coronavirus Disease 2019 (COVID-19). However, emerging evidence does not support direct infection of endothelial or other vascular wall cells and thus inflammation may be better… read more here.
Keywords: endothelial cells; infection; lung endothelial; cov infection ... See more keywords
Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co-cultured with Plasmodium falciparum field isolates
Sign Up to like & getrecommendations! Published in 2017 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-017-2552-0
Abstract: BackgroundPlasmodium falciparum infection can progress unpredictably to severe forms including respiratory distress and cerebral malaria. The mechanisms underlying the variable natural course of malaria remain elusive.MethodsThe cerebral microvascular endothelial cells-D3 and lung endothelial cells both… read more here.
Keywords: apoptosis; lung endothelial; microvascular endothelial; brain ... See more keywords
Effects of cognate, non-cognate and synthetic CXCR4 and ACKR3 ligands on human lung endothelial cell barrier function
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DOI: 10.1371/journal.pone.0187949
Abstract: Recent evidence suggests that chemokine CXCL12, the cognate agonist of chemokine receptors CXCR4 and ACKR3, reduces thrombin-mediated impairment of endothelial barrier function. A detailed characterization of the effects of CXCL12 on thrombin-mediated human lung endothelial… read more here.
Keywords: lung endothelial; cxcr4 ackr3; barrier function; cxcl12 ... See more keywords
Targeting the lung endothelial niche to promote angiogenesis and regeneration: A review of applications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1093369
Abstract: Lung endothelial cells comprise the pulmonary vascular bed and account for the majority of cells in the lungs. Beyond their role in gas exchange, lung ECs form a specialized microenvironment, or niche, with important roles… read more here.
Keywords: regeneration; lung endothelial; niche; lung ... See more keywords
Editorial: Molecular mechanisms of lung endothelial permeability
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.976873
Abstract: Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, United States, Division of Critical Care Medicine, Department of Pediatrics, University of Colorado Denver,… read more here.
Keywords: molecular mechanisms; editorial molecular; lung endothelial; mechanisms lung ... See more keywords