circCIMT Silencing Promotes Cadmium‐Induced Malignant Transformation of Lung Epithelial Cells Through the DNA Base Excision Repair Pathway (Adv. Sci. 14/2023)
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DOI: 10.1002/advs.202206896
Abstract: Malignant Transformation of Cells Cadmium (Cd) exposure derived from air pollution and smoking may cause lung cancer. In article number 2206896, Lihua Huang, Yiguo Jiang, and co‐workers reveal the mechanism of the role of circRNA… read more here.
Keywords: transformation lung; lung; lung epithelial; malignant transformation ... See more keywords
Lung epithelial cells: upstream targets in type 2-high asthma.
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DOI: 10.1002/eji.202250106
Abstract: Over the last years, technological advances in the field of asthma have led to the identification of two disease endotypes, namely type 2-high and type 2-low asthma, characterized by different pathophysiologic mechanisms at a cellular… read more here.
Keywords: asthma; lung epithelial; epithelial cells; type high ... See more keywords
PU.1 and epigenetic signals modulate 1,25‐dihydroxyvitamin D3 and C/EBPα regulation of the human cathelicidin antimicrobial peptide gene in lung epithelial cells
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DOI: 10.1002/jcp.27702
Abstract: LL‐37, the only known human cathelicidin which is encoded by the human antimicrobial peptide (CAMP) gene, plays a critical role in protection against bacterial infection. We previously demonstrated that cathelicidin is induced by 1,25‐dihydroxyvitamin D3… read more here.
Keywords: cathelicidin; epithelial cells; camp; lung epithelial ... See more keywords
Akt‐independent effects of triciribine on ACE2 expression in human lung epithelial cells: Potential benefits in restricting SARS‐CoV2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30343
Abstract: The severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019 (COVID‐19) binds to the angiotensin‐converting enzyme 2 (ACE2) to gain cellular entry. Akt inhibitor triciribine (TCBN) has demonstrated promising results in promoting recovery… read more here.
Keywords: epithelial cells; lung epithelial; ace2 expression; expression human ... See more keywords
Cigarette smoke alters the secretome of lung epithelial cells
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DOI: 10.1002/pmic.201600243
Abstract: Cigarette smoke is the most relevant risk factor for the development of lung cancer and chronic obstructive pulmonary disease. Many of its more than 4500 chemicals are highly reactive, thereby altering protein structure and function.… read more here.
Keywords: epithelial cells; cells cigarette; lung epithelial; cigarette smoke ... See more keywords
Lungosphere Assay: 3D Culture of Lung Epithelial Stem/Progenitor Cells.
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DOI: 10.1007/978-1-4939-7021-6_11
Abstract: Lung epithelium contains distinctive subpopulations of lung stem/progenitor cells (LSPCs) that are essential for lung epithelial maintenance and repair in vivo. Hence, LSPCs are in the center of interest of lung biology due to their… read more here.
Keywords: lung epithelial; stem progenitor; biology; lung ... See more keywords
The Inflammatory Effect of Iron Oxide and Silica Particles on Lung Epithelial Cells
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DOI: 10.1007/s00408-019-00200-z
Abstract: PurposeOur understanding of the respiratory health consequences of geogenic (earth-derived) particulate matter (PM) is limited. Recent in vivo evidence suggests that the concentration of iron is associated with the magnitude of the respiratory response to… read more here.
Keywords: epithelial cells; response; iron oxide; lung epithelial ... See more keywords
PD-L1 Regulates Inflammation in LPS-Induced Lung Epithelial Cells and Vascular Endothelial Cells by Interacting with the HIF-1α Signaling Pathway.
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DOI: 10.1007/s10753-021-01474-3
Abstract: Sepsis-induced lung injury was the most common cause of death in patients. This study aimed to investigate whether PD-L1 regulates the inflammation in LPS-induced lung epithelial cells and vascular endothelial cells by interacting with the… read more here.
Keywords: epithelial cells; lps induced; vascular endothelial; lung epithelial ... See more keywords
Graphene-induced apoptosis in lung epithelial cells through EGFR
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DOI: 10.1007/s11051-017-3957-9
Abstract: Expanding interest in nanotechnology applied to electronic and biomedical fields has led to fast-growing development of various nanomaterials. Graphene is a single-atom thick, two-dimensional sheet of hexagonally arranged carbon atoms with unique physical and chemical… read more here.
Keywords: apoptosis lung; apoptosis; lung epithelial; graphene induced ... See more keywords
The toxicological analysis of secondary organic aerosol in human lung epithelial cells and macrophages
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DOI: 10.1007/s11356-019-05317-5
Abstract: Secondary organic aerosol (SOA) is a component of airborne particulate matter in urban areas. However, their toxicities remain incompletely understood. In this study, we investigated the oxidative and inflammatory potency of SOA derived from three… read more here.
Keywords: epithelial cells; cells macrophages; lung epithelial; secondary organic ... See more keywords
Between life and death: Epithelial cells in lung pathologies.
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DOI: 10.1016/j.cellsig.2020.109652
Abstract: Recent lineage tracing strategies, single-cell RNA sequencing approaches and high-resolution imaging identified remarkable heterogeneity of lung epithelial cells thus leaving open a question as to their specific functions in lung health and disease. Understanding the… read more here.
Keywords: death epithelial; epithelial cells; cells lung; lung epithelial ... See more keywords