IL‐7 induces type 2 cytokine response in lung ILC2s and regulates GATA3 and CD25 expression
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab1220-819rrr
Abstract: Interleukin‐7 is a cytokine with well‐established roles in lymphocyte development and more recently, an expanded role in immune function. IL‐7Rα is highly expressed by innate lymphoid cells (ILCs), but how IL‐7 directs the development or… read more here.
Keywords: gata3 cd25; lung ilc2s; cd25 expression; expression ... See more keywords
IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s.
Sign Up to like & getrecommendations! Published in 2019 at "International immunology"
DOI: 10.1093/intimm/dxz077
Abstract: Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory disease. IQ motif-containing GTPase-activating protein 1 (IQGAP1) is a ubiquitously expressed scaffold… read more here.
Keywords: lung ilc2s; containing gtpase; gtpase activating; ilc2s ... See more keywords