An extracellular vesicular mutant KRAS‐associated protein complex promotes lung inflammation and tumor growth
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12307
Abstract: Abstract Extracellular vesicles (EVs) contain more than 100 proteins. Whether there are EVs proteins that act as an ‘organiser’ of protein networks to generate a new or different biological effect from that identified in EV‐producing… read more here.
Keywords: protein complex; inflammation; mutant kras; lung inflammation ... See more keywords
Gossypin exert lipopolysaccharide induced lung inflammation via alteration of Nrf2/HO-1 and NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental toxicology"
DOI: 10.1002/tox.23806
Abstract: Acute Lung Injury (ALI) is a critical medical condition that induces the injury into the lung tissue, resulting in decreased the oxygen levels in the circulation and finally causes the respiratory failure. In this study,… read more here.
Keywords: lung tissue; gossypin; lung; lung inflammation ... See more keywords
Lack of CD34 produces defects in platelets, microparticles, and lung inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Cell and Tissue Research"
DOI: 10.1007/s00441-020-03243-4
Abstract: Lung innate immune activation results in acute lung inflammation, which is characterized by alveolar barrier disruption and accumulation of cellular lung aggregates comprising neutrophils, platelets, mononuclear cells, and microparticles. CD34 is a sialomucin, with pan-selectin… read more here.
Keywords: cd34; lung injury; platelet; lung inflammation ... See more keywords
Artesunate Inhibits Renal Ischemia Reperfusion-Stimulated Lung Inflammation in Rats by Activating HO-1 Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0669-3
Abstract: ABSTRACTArtesunate (AS), a semi-synthetic derivative of Artemisia, has been shown to exert a wide range of pharmacological effects, such as anti-inflammatory and antioxidant functions. However, the protective functions of AS on renal ischemia reperfusion injury… read more here.
Keywords: biochemistry; stimulated lung; renal ischemia; inflammation ... See more keywords
Methods to evaluate virus-mediated acute lung inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Methods in Cell Biology"
DOI: 10.1016/bs.mcb.2021.12.021
Abstract: As more infectious viruses emerge that result in respiratory illness, there is a significant need to standardize airway harvests and maximize data acquisition. Animal models of respiratory viral infections have been outlined to allow for… read more here.
Keywords: acute lung; lung inflammation; methods evaluate; evaluate virus ... See more keywords
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.186
Abstract: Oncostatin M (OSM) is involved in pathogenesis of several human inflammatory diseases including lung inflammation and fibrosis. Although accumulating evidence indicates that OSM mediates lung inflammation, the precise mechanism for OSM on lung inflammation still… read more here.
Keywords: tnf receptor; inflammation; lung inflammation; receptor associated ... See more keywords
Rosuvastatin suppresses cytokine production and lung inflammation in asthmatic, hyperlipidemic and asthmatic-hyperlipidemic rat models.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.154993
Abstract: BACKGROUND Given the role that T lymphocytes play on the pathogenesis of allergic asthma, drugs targeting Th2 and Th17 cells may be a hopeful therapeutic strategy. This study aimed to evaluate the effect of rosuvastatin… read more here.
Keywords: rosuvastatin; asthmatic hyperlipidemic; lung inflammation; cytokine production ... See more keywords
Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2020.08.009
Abstract: Abstract To improve the efficacy of nucleic acid-based therapeutics, e.g., small interfering RNA (siRNA), transfection agents are needed for efficient delivery into cells. Several classes of dendrimers have been found useful as transfection agents for… read more here.
Keywords: tnf; delivery; pamam; sirna ... See more keywords
Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2019.103266
Abstract: The toxicological potential of halloysite nanotubes (HNTs) and variants after functional alterations to surface area are not clear. We assessed the toxicological response to HNTs (NaturalNano (NN)) before and after surface etching (NN-etched). Potential cytotoxicity… read more here.
Keywords: acute phase; response; surface area; area ... See more keywords
RhoA inhibitor suppresses the production of microvesicles and rescues high ventilation induced lung injury.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.03.059
Abstract: Microvesicles (MVs) have been extensively identified in various biological fluids including bronchoalveolar lavage fluid (BALF), peripheral blood and ascitic fluids. Our previous study showed that MVs are responsible for acute lung injury, but the exact… read more here.
Keywords: production; rhoa; rock; lung injury ... See more keywords
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2021.115674
Abstract: Chronic obstructive pulmonary disease (COPD) with increased morbidity and mortality is a worldwide healthcare challenge closely associated with cigarette smoking (CS). Currently, there is no effective therapeutic strategy to control inflammation in COPD patients. The… read more here.
Keywords: cigarette smoke; copd; induced lung; nlrp3 inflammasome ... See more keywords