Biomimetic In Vitro Lung Models: Current Challenges and Future Perspective
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210519
Abstract: As post‐COVID complications, chronic respiratory diseases are one of the foremost causes of mortality. The quest for a cure for this recent global challenge underlines that the lack of predictive in vitro lung models is… read more here.
Keywords: vitro; lung models; models current; biomimetic vitro ... See more keywords
Abstract LB417: Leveraging advanced human lung models to explore mechanisms underlying T-DXd-associated interstitial lung disease (ILD)
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-lb417
Abstract: Trastuzumab deruxtecan (T-DXd) is a HER2-directed antibody-drug conjugate approved for several indications, including HER2-positive unresectable or metastatic breast cancer that progressed on two or more prior therapies, HER2-positive locally advanced or metastatic gastric or gastroesophageal… read more here.
Keywords: human lung; dxd; lung; lung models ... See more keywords
Abstract Tu0059: Title: Adrenomedullin Enhances Vascular Integrity and Endothelial Cell Maturation in Bioengineered Lung Models
Sign Up to like & getrecommendations! Published in 2025 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atv.45.suppl_1.tu0059
Abstract: Rationale: The study of pulmonary vasculature diseases has been hindered by the limitations of ex vivo vascular models, which often fail to replicate the native vasculature. Paracrine signaling plays a key role in regulating endothelial… read more here.
Keywords: lung; lung models; integrity; cell ... See more keywords
Fabrication and Characterization of 3D Bioprinted Triple-layered Human Alveolar Lung Models
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Bioprinting"
DOI: 10.18063/ijb.v7i2.332
Abstract: The global prevalence of respiratory diseases caused by infectious pathogens has resulted in an increased demand for realistic in-vitro alveolar lung models to serve as suitable disease models. This demand has resulted in the fabrication… read more here.
Keywords: triple layered; human alveolar; fabrication; alveolar lung ... See more keywords
Advancements in 3D lung models for minimally invasive lung cancer surgery: from static to real-time dynamic modeling
Sign Up to like & getrecommendations! Published in 2025 at "Translational Lung Cancer Research"
DOI: 10.21037/tlcr-2025-460
Abstract: Three-dimensional (3D) lung models have become a valuable tool in surgical planning and intraoperative navigation by providing detailed visualizations of pulmonary structures (e.g., bronchial tree, pulmonary vasculature, lung parenchyma, and tumor). These models are useful… read more here.
Keywords: minimally invasive; invasive lung; lung; lung cancer ... See more keywords
Lung Models to Evaluate Silver Nanoparticles’ Toxicity and Their Impact on Human Health
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12132316
Abstract: Nanomaterials (NMs) solve specific problems with remarkable results in several industrial and scientific areas. Among NMs, silver nanoparticles (AgNPs) have been extensively employed as drug carriers, medical diagnostics, energy harvesting devices, sensors, lubricants, and bioremediation.… read more here.
Keywords: lung models; health; human health; toxicity ... See more keywords