Lung organoid simulations for modelling and predicting the effect of mutations on SARS-CoV-2 infectivity
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2021.03.020
Abstract: The global pandemic caused by the SARS-CoV-2 virus continues to spread. Infection with SARS- CoV-2 causes COVID-19, a disease of variable severity. Mutation has already altered the SARS-CoV-2 genome from its original reported sequence and… read more here.
Keywords: mutations sars; lung organoid; infectivity; cov infectivity ... See more keywords
Open questions in human lung organoid research
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1083017
Abstract: Organoids have become a prominent model system in pulmonary research. The ability to establish organoid cultures directly from patient tissue has expanded the repertoire of physiologically relevant preclinical model systems. In addition to their derivation… read more here.
Keywords: human lung; open questions; lung organoid; questions human ... See more keywords