Developmental mechanisms and adult stem cells for therapeutic lung regeneration.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.09.016
Abstract: Chronic degenerative lung diseases are essentially untreatable pathological conditions. By contrast, the healthy lung has numerous mechanisms that allow for rapid repair and restoration of function following minor acute injuries. We discuss the normal endogenous… read more here.
Keywords: regeneration developmental; developmental mechanisms; lung regeneration; therapeutic lung ... See more keywords
Lung Regeneration by Transplantation of Allogeneic Lung Progenitors Using a Safer Conditioning Regimen and Clinical-grade Reagents
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szab016
Abstract: Abstract Over the last decades, several studies demonstrated the possibility of lung regeneration through transplantation of various lung progenitor populations. Recently, we showed in mice that fetal or adult lung progenitors could potentially provide donor… read more here.
Keywords: lung; lung regeneration; lung progenitors; regeneration transplantation ... See more keywords
Developmental switch from morphological replication to compensatory growth for salamander lung regeneration
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DOI: 10.1111/cpr.13369
Abstract: Salamanders possess a pair of lungs for active air breathing, but the lung respiration is fully operational only during the late stage of development, particularly after metamorphosis. Larval salamanders mainly exchange air through the gills… read more here.
Keywords: lung; compensatory growth; lung regeneration; morphological replication ... See more keywords
SARS-CoV-2 Infection and Lung Regeneration
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DOI: 10.1128/cmr.00188-21
Abstract: The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced immunopathology whereby the virus enters the host cells by binding to angiotensin-converting enzyme 2 (ACE2). Sophisticated regeneration and repair programs exist… read more here.
Keywords: lung regeneration; immunopathology; lung; cov infection ... See more keywords