LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "lung specific" as a keyword



Lung‐specific exosomes for doxorubicin delivery in lung adenocarcinoma therapy

Sign Up to like & get
recommendations! Published in 2024 at "Biotechnology Journal"

DOI: 10.1002/biot.202300296

Abstract: Doxorubicin (DOX) could be utilized to treat lung adenocarcinoma (LUAD), while dose‐limiting cardiotoxicity limits its clinical utilization. MDA‐MB‐231 cell‐derived exosomes show lung‐specific organotropism features. In this study, we aimed to explore the potential of MDA‐MB‐231… read more here.

Keywords: lung; lung specific; lung adenocarcinoma; delivery ... See more keywords

Helper-Polymer Based Five-Element Nanoparticles (FNPs) for Lung-Specific mRNA Delivery with Long-Term Stability after Lyophilization.

Sign Up to like & get
recommendations! Published in 2022 at "Nano letters"

DOI: 10.1021/acs.nanolett.2c01784

Abstract: Lipid nanoparticles (LNPs) carrying therapeutic mRNAs hold great promise in treating lung-associated diseases like viral infections, tumors, and genetic disorders. However, because of their thermodynamically unstable nature, traditional LNPs carrying mRNAs need to be stored… read more here.

Keywords: specific mrna; mrna delivery; lung specific; lung ... See more keywords

A lung-specific mutational signature enables inference of viral and bacterial respiratory niche.

Sign Up to like & get
recommendations! Published in 2023 at "Microbial genomics"

DOI: 10.1099/mgen.0.001018

Abstract: Exposure to different mutagens leaves distinct mutational patterns that can allow inference of pathogen replication niches. We therefore investigated whether SARS-CoV-2 mutational spectra might show lineage-specific differences, dependent on the dominant site(s) of replication and… read more here.

Keywords: mutational signature; specific mutational; enables inference; lung specific ... See more keywords

Tuning Design Parameters of ICAM-1-Targeted 3DNA Nanocarriers to Optimize Pulmonary Targeting Depending on Drug Type

Sign Up to like & get
recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14071496

Abstract: 3DNA holds promise as a carrier for drugs that can be intercalated into its core or linked to surface arms. Coupling 3DNA to an antibody targeting intercellular adhesion molecule 1 (ICAM-1) results in high lung-specific… read more here.

Keywords: icam targeted; lung specific; design parameters; drug ... See more keywords