LAUSR

Lung targeted liposomes for treating ARDS

Sign Up to like & get
recommendations!
3 Published in 2022 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2022.03.028

Abstract: Acute Respiratory Distress Syndrome (ARDS), associated with Covid-19 infections, is characterized by diffuse lung damage, inflammation and alveolar collapse that impairs gas exchange, leading to hypoxemia and patient’ mortality rates above 40%. Here, we describe… read more here.

Keywords: lung; treating ards; inflamed lungs; lung targeted ... See more keywords

Polymer-Based Novel Lung Targeted Delivery Systems.

Sign Up to like & get
recommendations!
0 Published in 2017 at "Current pharmaceutical design"

DOI: 10.2174/1381612822666161027104304

Abstract: BACKGROUND Due to its unique features, the respiratory tract had received great attention as a promising non-invasive route for drug administration to achieve both local and systemic effects. Efforts spent to tailor systems able to… read more here.

Keywords: lung targeted; delivery systems; polymer based; targeted delivery ... See more keywords

Lung-Targeted Delivery of Dimethyl Fumarate Promotes the Reversal of Age-Dependent Established Lung Fibrosis

Sign Up to like & get
recommendations!
1 Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11030492

Abstract: Idiopathic pulmonary fibrosis (IPF), a severe and deadly form of lung fibrosis, is widely regarded as a disease of aging. We previously demonstrated that aged mice with persistent lung fibrosis and IPF lung myofibroblasts exhibit… read more here.

Keywords: lung fibrosis; lung targeted; age; lung ... See more keywords

Lung Targeted Lipopolymeric Microspheres of Dexamethasone for the Treatment of ARDS

Sign Up to like & get
recommendations!
0 Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13091347

Abstract: Acute respiratory distress syndrome (ARDS), a catastrophic illness of multifactorial etiology, involves a rapid upsurge in inflammatory cytokines that leads to hypoxemic respiratory failure. Dexamethasone, a synthetic corticosteroid, mitigates the glucocorticoid-receptor-mediated inflammation and accelerates tissue… read more here.

Keywords: lung targeted; treatment; targeted lipopolymeric; dexamethasone ... See more keywords

Systematic Assessment of Strategies for Lung-targeted Delivery of MicroRNA Mimics

Sign Up to like & get
recommendations!
0 Published in 2018 at "Theranostics"

DOI: 10.7150/thno.22912

Abstract: There is considerable interest in the use of synthetic miRNA mimics (or inhibitors) as potential therapeutic agents in pulmonary vascular disease; however, the optimal delivery method to achieve high efficiency, selective lung targeting has not… read more here.

Keywords: lung targeted; fold lower; delivery; cel mir ... See more keywords