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   Articles with "lung targeting" as a keyword



A Comparison of Two Methods for the Preparation Cefquinome-Loaded Gelatin Microspheres for Lung Targeting

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recommendations! Published in 2018 at "Pharmaceutical Research"

DOI: 10.1007/s11095-018-2342-4

Abstract: PurposeThe aim of this study was to prepare CEQ-loaded gelatin microspheres and compare two preparation methods, evaluate targeting to the lungs.MethodsGelatin microspheres containing CEQ were prepared by an emulsion cross-linking method (ECLM) and a spray-drying… read more here.

Keywords: gelatin microspheres; ceq; lung targeting; loaded gelatin ... See more keywords

The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo

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recommendations! Published in 2023 at "Nano Letters"

DOI: 10.1021/acs.nanolett.2c04479

Abstract: Lipid nanoparticles (LNPs) have delivered RNA to hepatocytes in patients, underscoring the potential impact of nonliver delivery. Scientists can shift LNP tropism to the lung by adding cationic helper lipids; however, the biological response to… read more here.

Keywords: transcriptional response; response lung; lung; lung targeting ... See more keywords

A novel phenolic propanediamine moiety-based lung-targeting therapy for asthma

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recommendations! Published in 2018 at "Drug Delivery"

DOI: 10.1080/10717544.2018.1472675

Abstract: Abstract Asthma is one of the most prevalent chronic inflammatory diseases of lung. Current asthma therapy using inhaled corticosteroid often results in undesired treatment outcome due to poor compliance and drugs’ lack of tissue specificity.… read more here.

Keywords: propanediamine; lung targeting; therapy; rhein ... See more keywords

Lung-Targeting Cepharanthine Polymer Micelles Modified with Mannose: Effectiveness Against Acute Lung Injury Evaluated Using in vitro and in vivo Analyses.

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recommendations! Published in 2025 at "Current drug metabolism"

DOI: 10.2174/0113892002413042251015104239

Abstract: Introduction: The currently available therapies for acute lung injury (ALI), including gluco-corticoids, protease inhibitors, and heparin, have limited clinical efficacy and are often associated with significant side effects. Cepharanthine (CEP) has demonstrated effectiveness in treating… read more here.

Keywords: cep pms; lung injury; lung targeting; lung ... See more keywords