Methanolic bark extract of Acacia catechu ameliorates benzo(a)pyrene induced lung toxicity by abrogation of oxidative stress, inflammation, and apoptosis in mice
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22382
Abstract: Benzo(a)pyrene [B(a)P] is a well‐known carcinogen present in the environment. In this study, we evaluated the protective potential of methanolic bark extract of Acacia catechu Willd. (MEBA) against the lung toxicity induced by B(a)P in… read more here.
Keywords: bark extract; toxicity; benzo pyrene; mice ... See more keywords
Lung Toxicity after Lenalidomide Treatment in a Patient with Multiple Myeloma.
Sign Up to like & getrecommendations! Published in 2017 at "Archivos de bronconeumologia"
DOI: 10.1016/j.arbres.2016.10.011
Abstract: Multiple myeloma is the second most common cancer of the blood. Despite significant advances in treatment, it is considered an incurable disease, response to treatment is limited in duration, and the clinical course is generally… read more here.
Keywords: multiple myeloma; treatment; lung toxicity; treatment patient ... See more keywords
42. The role of emphysema on radiation-induced lung toxicity and the feasibility of a “functional treatment plan”
Sign Up to like & getrecommendations! Published in 2018 at "Physica Medica"
DOI: 10.1016/j.ejmp.2018.04.052
Abstract: Purpose Although the relationship between pulmonary emphysema (PE) and pneumonitis after radiotherapy has been investigated in recent years, it remain controversial [1] , [2] . The aim of this study was to retrospectively examine the… read more here.
Keywords: radiation induced; rilt; treatment; feasibility functional ... See more keywords
Protective effects of febuxostat against paraquat‐induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades
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DOI: 10.1016/j.lfs.2019.02.007
Abstract: Aims: The herbicide paraquat causes fatal lung toxicity by induction of xanthine oxidase, production of free radicals and inflammation. Febuxostat, a xanthine oxidase inhibitor and anti‐gout has recently shown anti‐inflammatory activity. Accordingly, this study was… read more here.
Keywords: paraquat; pi3k akt; induced lung; paraquat induced ... See more keywords
Design and optimization of silymarin loaded in lyophilized fast melt tablets to attenuate lung toxicity induced via HgCl2 in rats
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DOI: 10.1080/10717544.2022.2068696
Abstract: Abstract The present study aimed to develop fast melting tablets (FMTs) using silymarin (SM) owing to FMTs rapid disintegration and dissolution. FMTs represent a pathway to help patients to increase their compliance level of treatment… read more here.
Keywords: optimization; silymarin; lung toxicity; lung ... See more keywords
The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2019.1687629
Abstract: Abstract Lead (Pb) is recognized as the first heavy metal of the top six toxic air pollutants threatening human health and the second hazardous substance. Pb exposure is associated with lung impairment and high incidences… read more here.
Keywords: a549 cells; lung toxicity; lung cancer; lung ... See more keywords
Cone‐beam CT radiomics features might improve the prediction of lung toxicity after SBRT in stage I NSCLC patients
Sign Up to like & getrecommendations! Published in 2020 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.13349
Abstract: Stereotactic body radiotherapy (SBRT) is the standard care for inoperable early stage non‐small cell lung cancer (NSCLC). The purpose of our study was to investigate whether a prediction model based on cone‐beam CT (CBCT) plus… read more here.
Keywords: radiomics features; improve prediction; cone beam; lung toxicity ... See more keywords
Immunotherapy-Induced Airway Disease: A New Pattern of Lung Toxicity of Immune Checkpoint Inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "Respiration"
DOI: 10.1159/000504968
Abstract: Immune checkpoint inhibitors (ICIs) have been shown to improve overall and progression-free survival in various cancers but have been associated with various immune-related adverse events (IRAEs), including interstitial lung disease, especially organizing pneumonia. We report… read more here.
Keywords: immune checkpoint; airway disease; checkpoint inhibitors; pattern lung ... See more keywords
Acute Lung Toxicity After Intralesional Bleomycin Sclerotherapy
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DOI: 10.1542/peds.2016-1787
Abstract: In this article, we report the second case of lung toxicity observed after bleomycin intralesional administration, and the one reported after the lowest dose of the drug to date. Bleomycin has progressively been used to… read more here.
Keywords: toxicity; acute lung; lung toxicity; bleomycin sclerotherapy ... See more keywords
Does Gender Difference Effect Radiation-Induced Lung Toxicity? An Experimental Study by Genetic and Histopathological Predictors
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DOI: 10.1667/rade-21-00075.1
Abstract: Several studies have reported differences in radiation toxicity between the sexes, but these differences have not been tested with respect to histopathology and genes. This animal study aimed to show an association between histopathological findings… read more here.
Keywords: toxicity; radiation; induced lung; lung toxicity ... See more keywords
The Beneficial Effects of QIAPI 1® against Pentavalent Arsenic-Induced Lung Toxicity a Hypothetical Model for SARS CoV2-Induced Lung Toxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201022666210412142230
Abstract: Exposure to environmental toxicants such as Arsenic (As) can result in As-induced alterations in immune regulators. Consequently, people who are more prone to viral infections like influenza A or B, H1N1, SARS CoV (Severe Acute… read more here.
Keywords: sars cov2; toxicity; pathology; induced lung ... See more keywords