FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12200
Abstract: Gefitinib, an epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR‐TKI), is an effective treatment for non‐small‐cell lung cancer (NSCLC) with EGFR activating mutations, but inevitably, the clinical efficacy is impeded by the emergence of acquired resistance.… read more here.
Keywords: tumor development; gefitinib; lung tumor; therapy ... See more keywords
A new method for assessing lung tumor motion in radiotherapy using dynamic chest radiography
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13736
Abstract: Abstract Dynamic chest radiography (DCR) is a recent advanced modality to acquire dynamic and functional images. We developed a new method using DCR and the free analysis software, Kinovea, to assess lung tumor motion. This… read more here.
Keywords: tumor motion; motion; lung tumor; method ... See more keywords
Technical Note: A 3D-printed phantom for radiochromic film evaluation of moving lung tumor SBRT without dose convolution.
Sign Up to like & getrecommendations! Published in 2021 at "Medical physics"
DOI: 10.1002/mp.14841
Abstract: PURPOSE A common dosimetric quality-assurance (QA) method in stereotactic body radiation therapy (SBRT) of lung tumors is to use lung phantoms with radiochromic film. However, in most phantoms, the film moves with the tumor, leading… read more here.
Keywords: phantom; radiochromic film; technical note; film ... See more keywords
Survival Benefit of Radiofrequency Ablation with Intratumoral Cisplatin Administration in a Rabbit VX2 Lung Tumor Model
Sign Up to like & getrecommendations! Published in 2020 at "CardioVascular and Interventional Radiology"
DOI: 10.1007/s00270-020-02686-0
Abstract: This study evaluated the survival benefit of a combination therapy with radiofrequency ablation (RFA) and intratumoral cisplatin (ITC) administration for lung tumors by using a rabbit VX2 tumor model. Experiments were approved by the institutional… read more here.
Keywords: lung tumor; group; tumor model; tumor ... See more keywords
Conformity of Fine Needle Aspiration Biopsy (FNAB) and Core Needle Biopsy (CNB) in peripheral lung tumor patients: A cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2022.103423
Abstract: Background The problem of establishing lung tumor diagnostics is a challenge for clinicians, especially pulmonologists, in determining a definitive diagnosis of a lung tumor. Objective Analyzing the conformity of anatomical pathology results between fine-needle aspiration… read more here.
Keywords: pathology; conformity; biopsy; lung tumor ... See more keywords
[I008] Systematic evaluation of lung-tumor motion using four-dimensional computed tomography
Sign Up to like & getrecommendations! Published in 2018 at "Physica Medica"
DOI: 10.1016/j.ejmp.2018.06.080
Abstract: Purpose To establish a suitable routine for handling of internal patient motions during radiotherapy delivery it is valuable to have information on the actual motions in a large group of patients. This presentation focus on… read more here.
Keywords: motion; four dimensional; dimensional computed; lung tumor ... See more keywords
Lung Tumor Histology as a Prognostic Factor for Short‐ and Long‐Term Postoperative Outcomes: P12
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.07.051
Abstract: Background: Despite targeted therapies impacted on progression-free survival in EGFR positive metastatic NoneSmall Cell lung carcinoma (NSCLC) these agents are not available in brazilian public health care system (SUS). Polychemotherapy based on platinum still being… read more here.
Keywords: tumor histology; histology; prognostic factor; lung tumor ... See more keywords
Tumorigenic response in lung tumor susceptible A/J mice after sub-chronic exposure to calcium chromate or iron (III) oxide.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2020.09.012
Abstract: Iron oxides are Group 3 (not classifiable as to its carcinogenicity to humans) according to the International Agency for Research on Cancer (IARC). Occupational exposures during iron and steel founding and hematite underground mining as… read more here.
Keywords: exposure; mice; lung tumor; iron ... See more keywords
Using 4DCBCT simulation and guidance to evaluate inter-fractional tumor variance during SABR for lung tumor within the lower lobe
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99489-1
Abstract: Inter-fractional tumor variance would lead to insufficient dosage or overdose in tumor region during lung cancer radiotherapy. However, previous works have not considered influence of inter-fractional tumor amplitude variance at treatment position due to lack… read more here.
Keywords: fractional tumor; inter fractional; variance; lung tumor ... See more keywords
Transient Systemic Autophagy Ablation Irreversibly Inhibits Lung Tumor Cell Metabolism and Promotes T-Cell Mediated Tumor Killing.
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2141534
Abstract: Macroautophagy/autophagy is a highly conserved catabolic process pivotal to cellular homeostasis and support of tumorigenesis. Being a potential therapeutic target for cancer, we have worked to understand the implications of autophagy inhibition both systemically, and… read more here.
Keywords: cell; metabolism; transient systemic; lung tumor ... See more keywords
Combinatory lung tumor inhibition by myo-inositol and iloprost/rapamycin: association with immunomodulation.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac019
Abstract: Although both preclinical and clinical studies have suggested that myo-inositol (MI) may be a safe and effective lung cancer chemopreventive agent, its efficacy is moderate. To test whether the chemopreventive agents iloprost (IL) or rapamycin… read more here.
Keywords: lung; rapamycin; iloprost rapamycin; lung tumors ... See more keywords